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Review

Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation

1
Centre of Innovative Biotechnological Investigations “NANOLAB”, 197/2 Vernadsky Pr., Moscow 119571, Russia
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Medena AG., Industriestrasse 16, CH-8910 Affoltern-am-Abis, Switzerland
*
Author to whom correspondence should be addressed.
Academic Editor: Michael Breitenbach
Biomolecules 2017, 7(2), 40; https://doi.org/10.3390/biom7020040
Received: 4 April 2017 / Revised: 3 May 2017 / Accepted: 8 May 2017 / Published: 12 May 2017
Recently, aggressive advertisement claimed a “magic role” for plant stem cells in human skin rejuvenation. This review aims to shed light on the scientific background suggesting feasibility of using plant cells as a basis of anti-age cosmetics. When meristem cell cultures obtained from medicinal plants are exposed to appropriate elicitors/stressors (ultraviolet, ultrasound ultraviolet (UV), ultrasonic waves, microbial/insect metabolites, heavy metals, organic toxins, nutrient deprivation, etc.), a protective/adaptive response initiates the biosynthesis of secondary metabolites. Highly bioavailable and biocompatible to human cells, low-molecular weight plant secondary metabolites share structural/functional similarities with human non-protein regulatory hormones, neurotransmitters, pigments, polyamines, amino-/fatty acids. Their redox-regulated biosynthesis triggers in turn plant cell antioxidant and detoxification molecular mechanisms resembling human cell pathways. Easily isolated in relatively large quantities from contaminant-free cell cultures, plant metabolites target skin ageing mechanisms, above all redox imbalance. Perfect modulators of cutaneous oxidative state via direct/indirect antioxidant action, free radical scavenging, UV protection, and transition-metal chelation, they are ideal candidates to restore photochemical/redox/immune/metabolic barriers, gradually deteriorating in the ageing skin. The industrial production of plant meristem cell metabolites is toxicologically and ecologically sustainable for fully “biological” anti-age cosmetics. View Full-Text
Keywords: cosmetics; environmental stress; meristem plant cells; plant metabolites; polyphenols; RNS; ROS; skin photoageing; skin rejuvenation; UV cosmetics; environmental stress; meristem plant cells; plant metabolites; polyphenols; RNS; ROS; skin photoageing; skin rejuvenation; UV
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MDPI and ACS Style

Korkina, L.G.; Mayer, W.; De Luca, C. Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation. Biomolecules 2017, 7, 40. https://doi.org/10.3390/biom7020040

AMA Style

Korkina LG, Mayer W, De Luca C. Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation. Biomolecules. 2017; 7(2):40. https://doi.org/10.3390/biom7020040

Chicago/Turabian Style

Korkina, Liudmila G., Wolfgang Mayer, and Chiara De Luca. 2017. "Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation" Biomolecules 7, no. 2: 40. https://doi.org/10.3390/biom7020040

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