α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation
Abstract
1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Cell Culture
2.3. Polyamine Analysis
2.4. Statistical Analysis
3. Results
3.1. Effects of Thymidine and 1-MeSpd on Growth of DFMO-Treated Cells
3.2. Effects of L-Methionine and SAM on Growth of DFMO-Treated Cells
3.3. Effects of DFMO, Thymidine, L-Methionine and SAM on Polyamine Levels
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Hyvönen, M.T.; Khomutov, M.; Vepsäläinen, J.; Khomutov, A.R.; Keinänen, T.A. α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation. Biomolecules 2021, 11, 707. https://doi.org/10.3390/biom11050707
Hyvönen MT, Khomutov M, Vepsäläinen J, Khomutov AR, Keinänen TA. α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation. Biomolecules. 2021; 11(5):707. https://doi.org/10.3390/biom11050707
Chicago/Turabian StyleHyvönen, Mervi T., Maxim Khomutov, Jouko Vepsäläinen, Alex R. Khomutov, and Tuomo A. Keinänen. 2021. "α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation" Biomolecules 11, no. 5: 707. https://doi.org/10.3390/biom11050707
APA StyleHyvönen, M. T., Khomutov, M., Vepsäläinen, J., Khomutov, A. R., & Keinänen, T. A. (2021). α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation. Biomolecules, 11(5), 707. https://doi.org/10.3390/biom11050707