Correction: Khan et al. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276
Reference
- Khan, A.; Kanwal, F.; Ullah, S.; Fahad, M.; Tariq, L.; Altaf, M.T.; Riaz, A.; Zhang, G. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276. [Google Scholar] [CrossRef]
| Name | Related Functions | Plant Specie | References |
|---|---|---|---|
| Terpenes | |||
| Monoterpenes | Chemical products secreted by plants are important against insect toxicity | Chrysanthemum, cumin, pepper, mint, eucalyptus | [150] |
| Diterpenes | Act as epithelium irritants and toxins to insects and mammals | Codiaeum, Hura Phyllanthus | [151] |
| Triterpenes | Triterpenes have some self-protective effects against insects by altering their development | Higher plants Ferns and marine organisms | [152] |
| Polyterpenes | Offer defense as a process for infection repair and as resistance to pests | Bruce banner | [153] |
| Phenolics | |||
| Phenolics flavonoids Coumarin Bioflavonoids Others | Flavanol content is significantly lower under the lower temperature treatment in pygmy smartweed | Polygonum minus Huds. | [154] |
| - | HT has little effect on seed phenolics, but reduces anthocyanins in the skin of grapes | Vitis vinifera L. | [155] |
| - | Monoterpenes and sesquiterpenes increase in thyme in response to DS | Artemisia annua L. | [156] |
| - | Monosubstituted flavanols increase under UVB Flavanols are unaffected; supplemental UVB also increases tannins in some species | Tomato | [54] |
| Nitrogen-containing SMs | |||
| Alkaloids Cyanogenic glycosides Non-Protein Amino Acid | Cause signaling molecule to trigger flavonoid biosynthesis under lower temperatures | Apple (Malus sp.) | [54] |
| - | Increased light may have negative consequences on SM production in sensitive plants. Longer photoperiod | Ocimum basilicum L. | [157] |
| - | Plants have more cyanogenic glycosides; variability also observed in alkaloids, which increases in the shade in evergreen tropical trees | Tabernaemontana pachysiphon Stapf | [54] |
| - | Arabidopsis mutants lacking flavonoids; production mechanisms are hypersensitive to UVB radiation; flavonoid production is tolerant to typically lethal UVB levels | Arabidopsis thaliana | [158] |
| Sulfur-containing SMs | |||
| Glutathione | GSH acts as a growth regulator and during stress it acts as an antioxidant, strengthening the defense system of the plants | Spinach Avocados Okara | [159] |
| Glucosinolate GLS | Plays a role in defense by poisoning herbivore insects during damage and as a feeding repellent | Mustar Allium allylcysd plant | [160] |
| Phytoalexins | This is a common defense mechanism against insect pests in numerous plants | Grapevine Vitis vinifera | [161] |
| Defensins, thionins, and lectins | Defensins, thionine, and lectins are stimulated by numerous stresses and show resistance against them | Circulatory white blood cells and tissue cells, wheat, corn, and tomato | [162] |
| Stilbenes | |||
| Resveratrol and pterostilbene) | Increased stilbene accumulation, greater with UV-C compared to fungal inoculum, and shows resistance | Vitis vinifera cvs. Alphonse Lavallée, Dan Ben-Hanna | [163] |
| anthocyanins; flavonoids; hydroxycinnamic acids Napoleon | Increased stilbene accumulation, greater with UV-C compared to UV-B (3- and 2-fold, respectively), and shows resistance | V. vinifera cv. Sangiovese | [163] |
| Stilbenes | Downregulation of STS expression under both low and high temperatures, upregulation of STS expression in response to CuSO4, and shows resistance | V. vinifera cv. Cabernet Sauvignon | [163] |
| Mono-glucosylated derivative resveratrol (trans- and cis-piceid and trans- and cis-resveratroloside) | Increase in trans-resveratrol endogenous accumulation and decreased release into the culture medium Glucosides show response to stress | V. vinifera cv. Barbera | [163] |
| Curcuminoids | |||
| Curcumin | Physical and chemical defense against pathogens as well as other stresses | Curcuma longa. L. | [164] |
| Curcumin/bisdemethoxycurcumin | Volatile compound shows antibacterial mechanism against a wide distribution of Gram-positive bacteria, | Curcuma longa. L. | [165] |
| Demethoxycurcumin | which have antipathogenic action against fungi, bacteria, and other pathogen agents | Turmeric | [166] |
| Chitinases | |||
| Maize chitinase 2 gene | Secondary metabolites considered as molecular targets of selection in plant–pathogen interactions. | Transgenic maize plant | [167] |
| Chitinase I gene | Inhibits phytopathogenic fungi A. solani, R. solani, F. spp., and V. dahliae | Hordeum vulgare cultivar, Haider-93 | [96] |
| Rice class I chitinase gene (Rchit) | Resistance against late leaf spot, rust disease, and A. flavus infection | Oryza sativa (Rice) | [168] |
| Tobacco osmotin (ap24) and rice chitinase (chi 11) gene | Reduce sheath blight disease caused by R. solani | Nicotiana sp. (Tobacco) and Oryza sativa (Rice) | [169] |
| Rice chitinase-3 gene | Resistance against leaf spot in peanut by Cercospora arachidicola | Oryza sativa (Rice) | [170] |
| Peroxidase | |||
| Glutathione peroxidase | Causes a reduction in the substrate to convert H2O2 hydroperoxides into water or oxygen, and shows resistance | Nicotiana sp. (Tobacco) | [96] |
| Horseradish peroxidase | Plants have adopted peroxidase systems to show resistance against numerous stresses | Armoracia rusticana | [171] |
| Cytochrome c peroxidase | These enzymes use peroxides as an electron acceptor for a reduction in oxidative damage due to stress in plants | Yeast | [172] |
| Myeloperoxidase | Includes plant immune responses to biotic stresses | Spinach | [173] |
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Khan, A.; Kanwal, F.; Ullah, S.; Fahad, M.; Tariq, L.; Altaf, M.T.; Riaz, A.; Zhang, G. Correction: Khan et al. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276. Metabolites 2026, 16, 154. https://doi.org/10.3390/metabo16030154
Khan A, Kanwal F, Ullah S, Fahad M, Tariq L, Altaf MT, Riaz A, Zhang G. Correction: Khan et al. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276. Metabolites. 2026; 16(3):154. https://doi.org/10.3390/metabo16030154
Chicago/Turabian StyleKhan, Ameer, Farah Kanwal, Sana Ullah, Muhammad Fahad, Leeza Tariq, Muhammad Tanveer Altaf, Asad Riaz, and Guoping Zhang. 2026. "Correction: Khan et al. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276" Metabolites 16, no. 3: 154. https://doi.org/10.3390/metabo16030154
APA StyleKhan, A., Kanwal, F., Ullah, S., Fahad, M., Tariq, L., Altaf, M. T., Riaz, A., & Zhang, G. (2026). Correction: Khan et al. Plant Secondary Metabolites—Central Regulators Against Abiotic and Biotic Stresses. Metabolites 2025, 15, 276. Metabolites, 16(3), 154. https://doi.org/10.3390/metabo16030154

