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Open AccessCommunication

Is the Botryococcus braunii Dry Biomass an Adjuvant for Anti-UVB Topical Formulations?

1
Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil
2
Department of Health Sciences, Universidade Federal do Espírito Santo, São Mateus, 29932-540 Espírito Santo, Brazil
3
CBIOS–Universidade Lusófona’s Research Center for Biosciences and Health Technologies, 1749-024 Lisbon, Portugal
4
Biochemical and Pharmaceutical Technology Department, Faculty of Pharmaceutical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2020, 88(2), 22; https://doi.org/10.3390/scipharm88020022
Received: 7 April 2020 / Revised: 17 April 2020 / Accepted: 23 April 2020 / Published: 26 April 2020
(This article belongs to the Special Issue Functional Ingredients in Topical and Transdermal Delivery Systems)
Several topical products have been developed to avoid the harmful effects from ultraviolet (UV) radiation, such as sunscreens. Research for actives from natural sources is increasing due to the fact that chemical filters could induce adverse events. The microalgae Botryococcus braunii has potential interest in cosmetic applications. Specialized literature reported that B. braunii aqueous extract induced a reduction in skin dehydration and collagen production and promoted antioxidant activity. This research aimed to produce B. braunii biomass and to investigate its contribution regarding photoprotection. Formulations containing B. braunii dry biomass, with or without UV filters into vehicles composed of an emulsifying polymer or a self-emulsifying base, were evaluated in vitro by means of photoprotective activity and photostability. B. braunii dry biomass did not provide adequate photoprotection efficacy; however, it was observed that the self-emulsifying base promoted better sun protection factor (SPF) in comparison with the emulsifying polymer.
Keywords: Botryococcus braunii; microalgae; photoprotection; functional ingredient; UV radiation Botryococcus braunii; microalgae; photoprotection; functional ingredient; UV radiation
MDPI and ACS Style

Ariede, M.B.; Morocho-Jácome, A.L.; Candido, T.M.; Lourenço, F.R.; Kato, E.T.M.; Lima, F.V.; Rosado, C.; Velasco, M.V.R.; Carvalho, J.C.M.; Baby, A.R. Is the Botryococcus braunii Dry Biomass an Adjuvant for Anti-UVB Topical Formulations? Sci. Pharm. 2020, 88, 22.

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