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Abstract

Ligand Determinants of Drug Trapping in hERG Potassium Channels

1
Department of Pharmacology and Toxicology, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
2
Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(7), 226; https://doi.org/10.3797/scipharm.oephg.21.PO-27
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

Inhibition of hERG channels prolongs the ventricular action potential and correspondingly the QT-interval with the risk of torsade de pointes arrhythmias which may result in sudden cardiac death.[...]

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MDPI and ACS Style

WINDISCH, A.; SCHIESARO, A.; THAI, K.-M.; TIMIN, E.; HOHAUS, A.; ECKER, G.F.; HERING, S. Ligand Determinants of Drug Trapping in hERG Potassium Channels. Sci. Pharm. 2009, 77, 226. https://doi.org/10.3797/scipharm.oephg.21.PO-27

AMA Style

WINDISCH A, SCHIESARO A, THAI K-M, TIMIN E, HOHAUS A, ECKER GF, HERING S. Ligand Determinants of Drug Trapping in hERG Potassium Channels. Scientia Pharmaceutica. 2009; 77(Posters (PO)):226. https://doi.org/10.3797/scipharm.oephg.21.PO-27

Chicago/Turabian Style

WINDISCH, A., A. SCHIESARO, K.-M. THAI, E. TIMIN, A. HOHAUS, G. F. ECKER, and S. HERING. 2009. "Ligand Determinants of Drug Trapping in hERG Potassium Channels" Scientia Pharmaceutica 77, Posters (PO): 226. https://doi.org/10.3797/scipharm.oephg.21.PO-27

APA Style

WINDISCH, A., SCHIESARO, A., THAI, K. -M., TIMIN, E., HOHAUS, A., ECKER, G. F., & HERING, S. (2009). Ligand Determinants of Drug Trapping in hERG Potassium Channels. Scientia Pharmaceutica, 77(Posters (PO)), 226. https://doi.org/10.3797/scipharm.oephg.21.PO-27

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