Ligand Determinants of Drug Trapping in hERG Potassium Channels
by
A. WINDISCH
1,*, 
A. SCHIESARO
2,
K.-M. THAI
2,
E. TIMIN
1,
A. HOHAUS
1,
G. F. ECKER
2 and
S. HERING
1 1
Department of Pharmacology and Toxicology, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
2
Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090, Vienna, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(7), 226; https://doi.org/10.3797/scipharm.oephg.21.PO-27
Submission received: 16 April 2009
/
Accepted: 16 April 2009
/
Published: 16 April 2009
Excerpt
Note: In lieu of an abstract, this is an excerpt from the first page.
Inhibition of hERG channels prolongs the ventricular action potential and correspondingly the QT-interval with the risk of torsade de pointes arrhythmias which may result in sudden cardiac death.[...]
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MDPI and ACS Style
WINDISCH, A.; SCHIESARO, A.; THAI, K.-M.; TIMIN, E.; HOHAUS, A.; ECKER, G.F.; HERING, S. Ligand Determinants of Drug Trapping in hERG Potassium Channels. Sci. Pharm. 2009, 77, 226. https://doi.org/10.3797/scipharm.oephg.21.PO-27
AMA Style
WINDISCH A, SCHIESARO A, THAI K-M, TIMIN E, HOHAUS A, ECKER GF, HERING S. Ligand Determinants of Drug Trapping in hERG Potassium Channels. Scientia Pharmaceutica. 2009; 77(Posters (PO)):226. https://doi.org/10.3797/scipharm.oephg.21.PO-27
Chicago/Turabian StyleWINDISCH, A., A. SCHIESARO, K.-M. THAI, E. TIMIN, A. HOHAUS, G. F. ECKER, and S. HERING. 2009. "Ligand Determinants of Drug Trapping in hERG Potassium Channels" Scientia Pharmaceutica 77, Posters (PO): 226. https://doi.org/10.3797/scipharm.oephg.21.PO-27
