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Sci. Pharm.
Volume 77
Issue 7
10.3797/scipharm.oephg.21.PO-21
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Abstract

Transport of NSAIDs across the Blood-Brain Barrier in vitro

by
I. NOVAKOVA
1,
W. NEUHAUS
2,
M. SONNENBERG
2 and
C. R. NOE
1,*
1
Department of Medicinal Chemistry, University of Vienna, Pharmacy Center, Althanstraße 14, 1090 Vienna, Austria
2
PharmaCon GmbH, Riglergasse 4/5, 1180, Vienna, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(7), 220; https://doi.org/10.3797/scipharm.oephg.21.PO-21
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Abstract

The migration of substances between blood circulation and central nervous system (CNS) is regulated by the blood-brain barrier (BBB). Small lipophilic molecules such as carbon dioxide, oxygen or ethanol can pass the BBB by passive, transcellular diffusion, while the paracellular transport of hydrophilic substances is restricted by intercellular tight-junctions. Due to accessory transport systems the BBB is able to regulate specifically the permeation of substances (e.g. nutrients) [1].

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MDPI and ACS Style

NOVAKOVA, I.; NEUHAUS, W.; SONNENBERG, M.; NOE, C.R. Transport of NSAIDs across the Blood-Brain Barrier in vitro. Sci. Pharm. 2009, 77, 220. https://doi.org/10.3797/scipharm.oephg.21.PO-21

AMA Style

NOVAKOVA I, NEUHAUS W, SONNENBERG M, NOE CR. Transport of NSAIDs across the Blood-Brain Barrier in vitro. Scientia Pharmaceutica. 2009; 77(Posters (PO)):220. https://doi.org/10.3797/scipharm.oephg.21.PO-21

Chicago/Turabian Style

NOVAKOVA, I., W. NEUHAUS, M. SONNENBERG, and C. R. NOE. 2009. "Transport of NSAIDs across the Blood-Brain Barrier in vitro" Scientia Pharmaceutica 77, Posters (PO): 220. https://doi.org/10.3797/scipharm.oephg.21.PO-21

APA Style

NOVAKOVA, I., NEUHAUS, W., SONNENBERG, M., & NOE, C. R. (2009). Transport of NSAIDs across the Blood-Brain Barrier in vitro. Scientia Pharmaceutica, 77(Posters (PO)), 220. https://doi.org/10.3797/scipharm.oephg.21.PO-21

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