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Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential

1
Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
2
Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
*
Author to whom correspondence should be addressed.
Diseases 2018, 6(2), 50; https://doi.org/10.3390/diseases6020050
Received: 15 May 2018 / Revised: 6 June 2018 / Accepted: 7 June 2018 / Published: 13 June 2018
(This article belongs to the Special Issue Pathogenesis of Pancreatic Cancer)
Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer. Pancreatic cystic lesions (PCLs) with malignant potential include: mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasm), solid pseudopapillary tumors and cystic neuroendocrine tumors. This review summarizes the latest literature describing what is known about the pathogenesis and malignant potential of these PCLs, including unique epidemiological, radiological, histological, genetic and molecular characteristics. View Full-Text
Keywords: pancreatic cystic lesions; mucinous lesions; intraductal pancreatic mucinous neoplasm; mucinous cystic neoplasm; solid pseudo-papillary tumors; cystic neuroendocrine tumors; pancreatic ductal adenocarcinoma pancreatic cystic lesions; mucinous lesions; intraductal pancreatic mucinous neoplasm; mucinous cystic neoplasm; solid pseudo-papillary tumors; cystic neuroendocrine tumors; pancreatic ductal adenocarcinoma
MDPI and ACS Style

Pusateri, A.J.; Krishna, S.G. Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential. Diseases 2018, 6, 50.

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