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Monitoring System for Laboratory Mice Transportation: A Novel Concept for the Measurement of Physiological and Environmental Parameters

1
Fraunhofer-Institut für Biomedizinische Technik (IBMT), 66280 Sulzbach/Saar, Germany
2
ITAP (Instituto de las Tecnologías Avanzadas de la Producción)—Universidad de Valladolid, Paseo del Cauce 59, 47011 Valladolid, Spain
3
Luxembourg Centre for Systems Biomedicine, University of Luxembourg Esch-sur-Alzette L-4362, Luxembourg and Internal Medicine II, Saarland University Medical Center, 66421 Homburg, Germany
*
Author to whom correspondence should be addressed.
Electronics 2019, 8(1), 34; https://doi.org/10.3390/electronics8010034
Received: 14 November 2018 / Revised: 14 December 2018 / Accepted: 20 December 2018 / Published: 1 January 2019
(This article belongs to the Section Bioelectronics)
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Abstract

Laboratory mice are used in biomedical research as “models” for studying human disease. These mice may be subject to significant levels of stress during transportation that can cause alterations that could negatively affect the results of the performed investigation. Here, we present the design and realization of a prototypical transportation container for laboratory mice, which may contribute to improved laboratory animal welfare. This prototype incorporates electric potential integrated circuit (EPIC) sensors, which have been shown to allow the recording of physiological parameters (heart rate and breathing rate) and other sensors for recording environmental parameters during mouse transportation. This allows for the estimation of the stress levels suffered by mice. First experimental results for capturing physiological and environmental parameters are shown and discussed. View Full-Text
Keywords: Laboratory animal transportation; EPIC sensors; mice stress; physiological signal processing; noninvasive measurements; hardware implementation Laboratory animal transportation; EPIC sensors; mice stress; physiological signal processing; noninvasive measurements; hardware implementation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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González-Sánchez, C.; Fraile, J.-C.; Pérez-Turiel, J.; Damm, E.; Schneider, J.G.; Schmitt, D.; Ihmig, F.R. Monitoring System for Laboratory Mice Transportation: A Novel Concept for the Measurement of Physiological and Environmental Parameters. Electronics 2019, 8, 34.

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