Next Article in Journal
Review of Modern Techniques for the Assessment of Skin Hydration
Previous Article in Journal
The Potential Application of Spring Sargassum glaucescens Extracts in the Moisture-Retention of Keratinocytes and Dermal Fibroblast Regeneration after UVA-Irradiation
Article Menu

Export Article

Open AccessArticle

Is There a Relationship between Transepidermal Water Loss and Microbial Biodiversity on the Skin?

1
Research Centre, Pavane Consultants Ltd., Reading, Berkshire RG1 5SB, UK
2
Information Services, University College London, Gower Street, London WC1E 6BT, UK
Cosmetics 2019, 6(1), 18; https://doi.org/10.3390/cosmetics6010018
Received: 25 January 2019 / Revised: 18 February 2019 / Accepted: 6 March 2019 / Published: 9 March 2019
  |  
PDF [6715 KB, uploaded 9 March 2019]
  |  

Abstract

As described in previous work, TEWL (transepidermal water loss) is used as an indicator of skin barrier function and health by scientists at top research institutions. However, it is known to be unreliable because many other factors determine its value, such as humidity, temperature and moisture content of the skin. In this study, to help elucidate whether it is a good indicator of the health of skin, we used bivariate linear correlation analysis and the Pearson correlation coefficient to compare values of skin microbial biodiversity with TEWL. In 2017 in our previous work, microbial biodiversity was found to currently be the only reliable indicator of skin health. Diversity was also compared with moisture content and pH, along with TEWL vs. moisture. All data was taken from the use of human participants in our previous work in 2018. Results showed no linear correlation between microbial biodiversity and TEWL rates or any of the other variables. This suggests the need for researchers to make conclusions about TEWL rates and their meaning with regards to skin function and health, with caution. Future work should consider the possibility of non-linear relationships, use larger datasets and mitigate against the effect of non-normally distributed data. View Full-Text
Keywords: transepidermal water loss; skin microbiome; skin microbiome biodiversity; biodiversity; skin barrier health; correlation; measure skin health; diversity transepidermal water loss; skin microbiome; skin microbiome biodiversity; biodiversity; skin barrier health; correlation; measure skin health; diversity
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Wallen-Russell, C. Is There a Relationship between Transepidermal Water Loss and Microbial Biodiversity on the Skin? Cosmetics 2019, 6, 18.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Cosmetics EISSN 2079-9284 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top