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Utility of the Teslar Facial Massager for Skin Elasticity and the Mechanism of its Effects

1
Bionics Program, Tokyo University of Technology Graduate School, Tokyo 192-0982, Japan
2
School of Bioscience and Biotechnology, Tokyo University of Technology, Tokyo 192-0982, Japan
*
Author to whom correspondence should be addressed.
Cosmetics 2018, 5(3), 49; https://doi.org/10.3390/cosmetics5030049
Received: 1 July 2018 / Revised: 8 August 2018 / Accepted: 10 August 2018 / Published: 14 August 2018
The Teslar is a facial massager that emits a weak electric current, where users have reported a beneficial effect on skin elasticity with continued use. Accordingly, we conducted a clinical utility study and a comprehensive gene analysis, with cultured human fibroblasts to investigate the utility and mechanism of this treatment. In this clinical utility study, we found significant improvement in skin elasticity in Teslar treatments, compared to controls after two weeks of treatment. In cell experiments, we found that adenosine triphosphate synthesis and collagen contraction were promoted in fibroblasts cultured in type I collagen gel, following Teslar treatment. We considered that Teslar treatment exerted a structurally regenerative effect on the dermal matrix, based on the results of GeneChip® Expression Analysis. In particular, we demonstrated that Teslar treatment promotes type I collagen mRNA expression and fibulin-5/DANCE (Developmental arteries and neural crest EGF (epidermal growth factor)-like) mRNA expression and protein levels, which are reduced with aging. We also found increases in LTBP-3 (Latent TGF-β binding protein-3) and CSPG4 (Chondroitin sulfate proteoglycan 4) mRNA expression levels. Based on these results, we considered that Teslar treatment promoted dermal regeneration and recovery of skin elasticity. View Full-Text
Keywords: Teslar; skin elasticity; adenosine triphosphate (ATP); fibulin-5/DANCE Teslar; skin elasticity; adenosine triphosphate (ATP); fibulin-5/DANCE
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Maeda, K.; Koizumi, S.; Sano, T.; Yoshimura, A.; Kiriyama, H.; Mimura, S. Utility of the Teslar Facial Massager for Skin Elasticity and the Mechanism of its Effects. Cosmetics 2018, 5, 49.

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