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Open AccessArticle

New Method of Measurement of Epidermal Turnover in Humans

School of Bioscience and Biotechnology, Tokyo University of Technology, 1404-1 Katakuramachi, Hachioji City, Tokyo 192-0982, Japan
Cosmetics 2017, 4(4), 47; https://doi.org/10.3390/cosmetics4040047
Received: 24 September 2017 / Revised: 26 October 2017 / Accepted: 7 November 2017 / Published: 10 November 2017
This report describes a new and simple technique to detect alterations in the rate of turnover in the epidermis without using any toxic chemical, such as a radiolabeled material. The method involves measuring the time course of the decrease of darkening of an ultraviolet A-irradiated site, compared with a non-irradiated control site. The turnover time of the persistent pigmentation on the inner side of the male forearm was 36.2 ± 6.2 days (age: 37.3 ± 11.3 years, mean ± standard deviation, n = 6), which is in reasonable agreement with the epidermal turnover time previously measured by injecting [3H] thymidine into human skin. View Full-Text
Keywords: epidermal turnover; turnover time epidermal turnover; turnover time
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Maeda, K. New Method of Measurement of Epidermal Turnover in Humans. Cosmetics 2017, 4, 47.

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