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Applications of Microalgal Biotechnology for Disease Control in Aquaculture

Center of Excellence for Shrimp Molecular Biology and Biotechnology, Mahidol University, Bangkok 10400, Thailand
National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand Science Park, Pathumthani 12120, Thailand
Institute of Structural and Molecular Biology, University College London, London WC1E 6BT, UK
Author to whom correspondence should be addressed.
Biology 2018, 7(2), 24;
Received: 26 January 2018 / Revised: 3 April 2018 / Accepted: 10 April 2018 / Published: 12 April 2018
(This article belongs to the Special Issue Microalgal Biotechnology)
Aquaculture industries, and in particular the farming of fish and crustaceans, are major contributors to the economy of many countries and an increasingly important component in global food supply. However, the severe impact of aquatic microbial diseases on production performance remains a challenge to these industries. This article considers the potential applications of microalgal technology in the control of such diseases. At the simplest level, microalgae offer health-promoting benefits as a nutritional supplement in feed meal because of their digestibility and high content of proteins, lipids and essential nutrients. Furthermore, some microalgal species possess natural anti-microbial compounds or contain biomolecules that can serve as immunostimulants. In addition, emerging genetic engineering technologies in microalgae offer the possibility of producing ‘functional feed additives’ in which novel and specific bioactives, such as fish growth hormones, anti-bacterials, subunit vaccines, and virus-targeted interfering RNAs, are components of the algal supplement. The evaluation of such technologies for farm applications is an important step in the future development of sustainable aquaculture. View Full-Text
Keywords: aquaculture; chloroplast transformation; disease control; microalgae; nuclear transformation; vaccine aquaculture; chloroplast transformation; disease control; microalgae; nuclear transformation; vaccine
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Charoonnart, P.; Purton, S.; Saksmerprome, V. Applications of Microalgal Biotechnology for Disease Control in Aquaculture. Biology 2018, 7, 24.

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