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Biology 2015, 4(2), 264-281;

A Multi-Functional Tubulovesicular Network as the Ancestral Eukaryotic Endomembrane System

Centro Andaluz de Biologia del Desarollo (CABD), Universidad Pablo de Olavide, Carretera de Utrera km 1, Seville 41013, Spain
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Chris O'Callaghan
Received: 25 November 2014 / Accepted: 3 March 2015 / Published: 24 March 2015
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The origin of the eukaryotic endomembrane system is still the subject of much speculation. We argue that the combination of two recent hypotheses addressing the eukaryotic endomembrane’s early evolution supports the possibility that the ancestral membranes were organised as a multi-functional tubulovesicular network. One of the potential selective advantages provided by this organisation was the capacity to perform endocytosis. This possibility is illustrated by membrane organisations observed in current organisms in the three domains of life. Based on this, we propose a coherent model of autogenous eukaryotic endomembrane system evolution in which mitochondria are involved at a late stage. View Full-Text
Keywords: Eukaryogenesis; membrane system; evolution; hypothesis Eukaryogenesis; membrane system; evolution; hypothesis

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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González-Sánchez, J.C.; Costa, R.; Devos, D.P. A Multi-Functional Tubulovesicular Network as the Ancestral Eukaryotic Endomembrane System. Biology 2015, 4, 264-281.

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