Investigation of the Oxidation Mechanism of Dopamine Functionalization in an AZ31 Magnesium Alloy for Biomedical Applications
Abstract
:1. Introduction
2. Materials and Methods
2.1. Substrate
2.2. Coating Process
2.3. Characterization
2.4. Electrochemical Analysis
2.5. Cell Cultivation
2.6. Molecular Dynamics Simulation
3. Results
3.1. Characterization of the Coating
3.2. Electrochemical Properties
3.3. Cell Cultivation
3.4. Molecular Dynamics Simulation
4. Discussion
4.1. Characterization of the Coating
4.2. Electrochemical Properties
5. Conclusions
- The molecular dynamic simulation and FTIR analysis show an improvement in the deposition rate and the presence of polydopamine on the substrate.
- The addition of oxygen increases the impedance response of the AZ31 alloy.
- The formation of polydopamine with the presence of amino and hydroxyl functional groups on the surface of the material might be promising for the cell’s response. Further investigations focused on the cell viability and proliferation are necessary to confirm the biocompatibility of the coating.
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample | Rs (Ω cm2) | R (Ω cm2) | CPE (µMho/cm2) | N | Rl (Ω cm2) | L (H cm2) | X2 (<0.5) |
---|---|---|---|---|---|---|---|
AZ31 | 22.1 | 68.7 | 39.6 | 0.841 | 38.3 | 13.9 | 0.385 |
dopa | 13.152 | 31.44 | 50.83 | 0.652 | 15.408 | 71.52 | 0.427 |
dopa-O | 15.38 | 142.32 | 105.83 | 0.718 | 185.52 | 264 | 0.206 |
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Ghanbari, A.; Warchomicka, F.; Sommitsch, C.; Zamanian, A. Investigation of the Oxidation Mechanism of Dopamine Functionalization in an AZ31 Magnesium Alloy for Biomedical Applications. Coatings 2019, 9, 584. https://doi.org/10.3390/coatings9090584
Ghanbari A, Warchomicka F, Sommitsch C, Zamanian A. Investigation of the Oxidation Mechanism of Dopamine Functionalization in an AZ31 Magnesium Alloy for Biomedical Applications. Coatings. 2019; 9(9):584. https://doi.org/10.3390/coatings9090584
Chicago/Turabian StyleGhanbari, Arezoo, Fernando Warchomicka, Christof Sommitsch, and Ali Zamanian. 2019. "Investigation of the Oxidation Mechanism of Dopamine Functionalization in an AZ31 Magnesium Alloy for Biomedical Applications" Coatings 9, no. 9: 584. https://doi.org/10.3390/coatings9090584