Next Article in Journal
Design and Manufacture of a Novel Sunlight Guiding Panel
Next Article in Special Issue
Investigation of the Oxidation Mechanism of Dopamine Functionalization in an AZ31 Magnesium Alloy for Biomedical Applications
Previous Article in Journal
Preparation and Formula Analysis of Anti-Biofouling Titania–Polyurea Spray Coating with Nano/Micro-Structure
Previous Article in Special Issue
The Formation of Microcrystal in Helium Ion Irradiated Aluminum Alloy
Open AccessFeature PaperArticle

Tri-Functional Calcium-Deficient Calcium Titanate Coating on Titanium Metal by Chemical and Heat Treatment

Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Aichi 487-8501, Japan
*
Author to whom correspondence should be addressed.
Coatings 2019, 9(9), 561; https://doi.org/10.3390/coatings9090561
Received: 6 August 2019 / Revised: 26 August 2019 / Accepted: 27 August 2019 / Published: 3 September 2019
(This article belongs to the Special Issue Surface Engineering of Light Alloys)
The main problem of orthopedic and dental titanium (Ti) implants has been poor bone-bonding to the metal. Various coatings to improve the bone-bonding, including the hydroxyapatite and titania, have been developed, and some of them have been to successfully applied clinical use. On the other hand, there are still challenges to provide antibacterial activity and promotion of bone growth on Ti. It was shown that a calcium-deficient calcium titanate coating on Ti and its alloys exhibits high bone-bonding owing to its apatite formation. In this study, Sr and Ag ions, known for their promotion of bone growth and antibacterial activity, were introduced into the calcium-deficient calcium titanate by a three-step aqueous solution treatment combined with heat. The treated metal formed apatite within 3 days in a simulated body fluid and exhibited antibacterial activity to Escherichia coli without showing any cytotoxicity in MC3T3-E1 preosteoblast cells. Furthermore, the metal slowly released 1.29 ppm of Sr ions. The Ti with calcium-deficient calcium titanate doped with Sr and Ag will be useful for orthopedic and dental implants, since it should bond to bone because of its apatite formation, promote bone growth due to Sr ion release, and prevent infection owing to its antibacterial activity. View Full-Text
Keywords: antibacterial activity; bone growth; apatite formation; titanium; silver; strontium; calcium titanate; ion release; cytotoxicity; controlled release antibacterial activity; bone growth; apatite formation; titanium; silver; strontium; calcium titanate; ion release; cytotoxicity; controlled release
Show Figures

Graphical abstract

MDPI and ACS Style

Yamaguchi, S.; Thi Minh Le, P.; Ito, M.; Shintani, S.A.; Takadama, H. Tri-Functional Calcium-Deficient Calcium Titanate Coating on Titanium Metal by Chemical and Heat Treatment. Coatings 2019, 9, 561.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop