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Open AccessArticle

Bioceramic Layers with Antifungal Properties

National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, Magurele 077125, Romania
Department of Mechanics, University Politehnica of Bucharest, BN 002, 313 Splaiul Independentei, Sector 6, Bucharest 060042, Romania
Author to whom correspondence should be addressed.
Coatings 2018, 8(8), 276;
Received: 11 July 2018 / Revised: 30 July 2018 / Accepted: 3 August 2018 / Published: 8 August 2018
PDF [20924 KB, uploaded 8 August 2018]


The sol-gel method was used to synthesize the silver doped hydroxyapatite (Ag:HAp) gels in order to produce the antifungal composite layers. The pure Ti disks were used as the substrate for the composite layers. Important information about suspensions used to make Ag:HAp composite layers were obtained from an ultrasonic technique. The identification of the phase composition of the Ag:HAp composite layers was accomplished X-ray diffraction (XRD). The morphology and the thickness of the layers was evaluated using scanning electron microscopy (SEM). The uniform distribution of the constituent elements (Ag, Ca, P, and O) in both analyzed samples was observed. The antifungal activity of the samples against Candida albicans ATCC 10231 microbial strain were investigated immediately after their preparation and six months later. SEM and confocal laser scanning microscopy (CLSM) images showed that the composite layers at the two time intervals exhibited a strong antifungal activity against Candida albicans ATCC 10231 and completely inhibited the biofilm formation. View Full-Text
Keywords: hydroxyapatite; silver; layer; antifungal properties hydroxyapatite; silver; layer; antifungal properties

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Predoi, D.; Iconaru, S.L.; Predoi, M.V. Bioceramic Layers with Antifungal Properties. Coatings 2018, 8, 276.

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