Evaluation of Biocompatibility of 316 L Stainless Steels Coated with TiN, TiCN, and Ti-DLC Films

Round 1
Reviewer 1 Report
This manuscript is about the “Comparative Investigation on Biocompatibility of Stainless Steels Coated with TiN, TiCN, and Ti-DLC Films” which are presented by J. Lou et al. They have published a similar coating condition entitled “Comparative Investigation on the Tribological Performances of TiN, TiCN, and Ti-DLC Film-Coated Stainless Steel” by DOI: 10.1007/s11837-019-03718-y. However, here the biocompatibility of AISI 316 L, is investigated. The subject is interesting but some modifications are required.
- Writing must be improved.
- The abbreviations in the first presentation should be correctly defined.
- 316 L SS in the standard writing is AISI 316 L.
- In the abstract, the novelty is better highlighted by the quantity statement.
- at Introduction mention the effect of Cr and Mo on toxicity.
- The adhesion of the coating to the substrate is unclear.
- A corrosion test is highly recommended (potentiodynamic corrosion test)
- The polishing procedure must be defined. (Experimental)
- Figure 4 is unclear. (biocompatibility assay)
- The role and contribution of the TiC nanocluster must be demonstrated sharply. (conclusion)
- The effect of substrate is unclear.
End
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
Reviewer 2 Report
Authors should add to the title 316 L
...316 L Stainless Steels Coated with TiN, TiCN, and Ti-DLC Films
There is no data on substrate 316 L it is very important what was the thermal heat treatment of the initial substrate before PVD.
There is also no data on the PVD what kind of PVD do you use - sputtering??
In dental medicine usually use 304L while in orthopedics 316 L SS is the right one
Please explain which standard you use for cytotoxicity -biocompatibility assessment
ISO 10933-5
The manuscript is very similar to Comparative Investigation on Corrosion Resistance of Stainless
Steels coated with Titanium Nitride, Nitrogen Titanium
Carbide and Titanium-Diamond-like Carbon Films
Author Response
Please see the attachment.
Author Response File: Author Response.pdf