Effect of Ti Atoms on Néel Relaxation Mechanism at Magnetic Heating Performance of Iron Oxide Nanoparticles

Round 1

Reviewer 1 Report

The manuscript (coatings-1630032) describes about the importance of functionalization on magnetite NPs for in-vivo hyperthermia treatment. The role of Titanium doping and silica functionalization have been explained and performed well. However, following are few minor issues to be addressed before accepting it into publication.

1. Line 32-36: Since ref {1,2} are common, so can be placed in one time.
2. relevant article doi: 10.1016/j.jmst.2013.07.002 could be used here for align of magnetite domain.
3. Line 51: “Brownian relaxation”? Please check.
4. line 61: “hypertermia”? Please check.
5. line 72: “viscose” ? please check.
6. line 117: check the size of letters.
7. line 152: “remenance”?

Comments for author File: Comments.docx

Author Response

Thank you for your comments improving the study. Please see the attachment

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Reviewer 2 Report

The paper entitled "Enhancement of Neel relaxation at magnetic heating performance of iron oxide nanoparticles" by Can M.M. et al has been reviewed. Nowadays, numerous scientists concentrate on the study of materials used for the hyperthermia use. Thus, the importance of the study is evident. The obtained experimental results seem to be promising. But there are some remarks which should be taken into consideration before publication. These are given below. To begin with, there are errors in the English language that should be eliminated (for example, line 23; line 77; lines 87-90; lines 106-109; lines 125-129; lines 157-1260; line 165; line 171; line 185; line 197 and so on).

1.       More details about the home-made setup used for the magneto-thermal characterization should be given.
2.       The chemical reaction (1) is not written correctly.
3.       The explanation of the SAR value increasing for the coated particles with x=0.03 should be proposed (Table 1).
4.      It would be interesting to perform the comparison with the literature results concerning obtained values of SAR temperature difference.
5.    Line 179: what does “MNPs” mean? 

Author Response

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Reviewer 3 Report

Reviewed paper “Enhancement of Neel Relaxation at Magnetic Heating Perfor-2 mance of Iron Oxide Nanoparticles” deals with an interesting topic and can be interesting for readers of Coatings journal. However, I have some objections to the quality of the submitted paper.

English of the paper is rather poor – in my opinion the language of the paper should be a little improved. I am asking for corrections by a native speaker.

I have concerns that the proposed theme of the article is outdated and relates to a subject known and described in the literature many years ago. This is evidenced by the Introduction and the cited literature (References).

Introduction chapter should be strongly correct. Authors should include new information about topic of a paper. More information based on worldwide (global) study. This Introduction is based on old literature (more than 5 years old) and mainly on the achievements of researchers in Asia.

References chapter is sufficient but papers cited in the references 25 from all 28 are older then 5 years – these publications constitute over 89 % of all cited papers. It is necessary to modify the list of literature and consequently also the part of the paper entitled Intrduction.

It is therefore recommended that the paper should be thoroughly rebuilt and resubmitted for review. In my opinion, the paper in this form should be rejected.

Author Response

Thank you for your comments improving the study. Please see the attachment.

Author Response File: Author Response.docx

Round 2

Reviewer 3 Report

Reviewed paper “Enhancement of Neel Relaxation at Magnetic Heating Performance of Iron Oxide Nanoparticles” with corrected paper titled “Effect of Ti Atoms on Néel Relaxation Mechanism at Magnetic Heating Performance of Iron Oxide Nanoparticles” deals with an interesting topic and can be interesting for readers of Coatings journal.

Referring to my substantive reservations – the authors made the necessary modifications. They changed the text of the article and removed stylistic and grammatical errors.

Author reformatted and extended Introduction, Experimental, Results and Discussion and Conclusions chapters and body text of a whole paper. Author significantly reformat the entire article. They modified a list of a references by including the most recent relevant publications published in last years.

But after corrections the paper still needs to be improved in terms of:

• English of the paper is rather poor – in my opinion the language of the paper should be a little improved. I am asking for corrections by a native speaker.
• Edition form of the article and in particular of list of references should be correct.

The paper are interesting and the manuscript can be accepted for publication in Coatings journal after MINOR corrections.

Author Response

Thank you very much for your valuable comments. Please see the attachment.

Author Response File: Author Response.docx