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Article
Peer-Review Record

Potential of FTIR-Spectroscopy for Drugs Screening against Helicobacter pylori

Antibiotics 2020, 9(12), 897; https://doi.org/10.3390/antibiotics9120897
by Pedro S. Sampaio 1,2 and Cecília R. C. Calado 2,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Antibiotics 2020, 9(12), 897; https://doi.org/10.3390/antibiotics9120897
Submission received: 24 November 2020 / Revised: 8 December 2020 / Accepted: 9 December 2020 / Published: 12 December 2020
(This article belongs to the Special Issue Discovery of Novel Antibiotics)

Round 1

Reviewer 1 Report

In this manuscript the authors describe the potential application of FTIR-based analysis of drug MICs against H. pylori. This manuscript presents an early development of the idea with potential applications in laboratory. Although this technique provides some advantages but it cannot, at this stage, replace the standard MIC assay against the bacteria.

As this manuscript is a resubmitted one and the authors have mentioned clearly enough in this version of the manuscript about the potential and the limitation of this technique. Therefore it will be accepted once the author have again checked the grammar and sentences in the manuscript with an appropriate native language service.

Author Response

Subject: Resubmission of revised paper “Potential of FTIR-spectroscopy for drugs screening against Helicobacter pylori

 

Reviewer 1

We have the pleasure to submit the final version of the manuscript. We appreciated and thanks to all the reviewer’s comments that strongly contributed for the manuscript improvement.

Author Response File: Author Response.docx

Reviewer 2 Report

 

I recommend a few modification.

Double check the English.

Can you reexplain the paragraph: 3.5. Chemometrics analysis, it's not clear written 

Conclusion need to be short and clear. Please phrase 3 short conclusion.

 

 

Author Response

Subject: Resubmission of revised paper “Potential of FTIR-spectroscopy for drugs screening against Helicobacter pylori

 

Reviewer 2

We have the pleasure to submit the final version of the manuscript. We appreciated and thanks to all the reviewer’s comments that strongly contributed for the manuscript improvement.

Author Response File: Author Response.docx

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