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Antibiotics 2018, 7(3), 69; https://doi.org/10.3390/antibiotics7030069

Biogenic Nanosilver against Multidrug-Resistant Bacteria (MDRB)

Laboratory of Chemical Biology, Institute of Chemistry, State University of Campinas, Campinas 13083-970, Brazil
Present address: School of Bioprocess and Chemical Engineering, University College Dublin, Dublin D04 V1W8, Ireland
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Received: 28 June 2018 / Accepted: 31 July 2018 / Published: 2 August 2018
(This article belongs to the Special Issue Silver-Based Antimicrobials)
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Abstract

Multidrug-resistant bacteria (MDRB) are extremely dangerous and bring a serious threat to health care systems as they can survive an attack from almost any drug. The bacteria’s adaptive way of living with the use of antimicrobials and antibiotics caused them to modify and prevail in hostile conditions by creating resistance to known antibiotics or their combinations. The emergence of nanomaterials as new antimicrobials introduces a new paradigm for antibiotic use in various fields. For example, silver nanoparticles (AgNPs) are the oldest nanomaterial used for bactericide and bacteriostatic purposes. However, for just a few decades these have been produced in a biogenic or bio-based fashion. This review brings the latest reports on biogenic AgNPs in the combat against MDRB. Some antimicrobial mechanisms and possible silver resistance traits acquired by bacteria are also presented. Hopefully, novel AgNPs-containing products might be designed against MDR bacterial infections. View Full-Text
Keywords: silver nanoparticles; biological synthesis; multidrug-resistant bacteria silver nanoparticles; biological synthesis; multidrug-resistant bacteria
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Barros, C.H.N.; Fulaz, S.; Stanisic, D.; Tasic, L. Biogenic Nanosilver against Multidrug-Resistant Bacteria (MDRB). Antibiotics 2018, 7, 69.

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