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Antibiotics 2018, 7(3), 67;

The Pros and Cons of the Use of Laser Ablation Synthesis for the Production of Silver Nano-Antimicrobials

Dipartimento di Chimica, Università degli Studi di Bari “Aldo Moro”, via E. Orabona 4, 70126 Bari, Italy
Institute of Photonics and nanotechnology-National Research Council (IFN-CNR), Physics Department “M. Merlin”, Bari, Italy, via Amendola 173, 70126 Bari, Italy
Authors to whom correspondence should be addressed.
Received: 29 June 2018 / Revised: 23 July 2018 / Accepted: 27 July 2018 / Published: 28 July 2018
(This article belongs to the Special Issue Silver-Based Antimicrobials)
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Silver nanoparticles (AgNPs) are well-known for their antimicrobial effects and several groups are proposing them as active agents to fight antimicrobial resistance. A wide variety of methods is available for nanoparticle synthesis, affording a broad spectrum of chemical and physical properties. In this work, we report on AgNPs produced by laser ablation synthesis in solution (LASiS), discussing the major features of this approach. Laser ablation synthesis is one of the best candidates, as compared to wet-chemical syntheses, for preparing Ag nano-antimicrobials. In fact, this method allows the preparation of stable Ag colloids in pure solvents without using either capping and stabilizing agents or reductants. LASiS produces AgNPs, which can be more suitable for medical and food-related applications where it is important to use non-toxic chemicals and materials for humans. In addition, laser ablation allows for achieving nanoparticles with different properties according to experimental laser parameters, thus influencing antibacterial mechanisms. However, the concentration obtained by laser-generated AgNP colloids is often low, and it is hard to implement them on an industrial scale. To obtain interesting concentrations for final applications, it is necessary to exploit high-energy lasers, which are quite expensive. In this review, we discuss the pros and cons of the use of laser ablation synthesis for the production of Ag antimicrobial colloids, taking into account applications in the food packaging field. View Full-Text
Keywords: silver nanoparticles; laser ablation synthesis in solution; nano-antimicrobials; food packaging silver nanoparticles; laser ablation synthesis in solution; nano-antimicrobials; food packaging

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Sportelli, M.C.; Izzi, M.; Volpe, A.; Clemente, M.; Picca, R.A.; Ancona, A.; Lugarà, P.M.; Palazzo, G.; Cioffi, N. The Pros and Cons of the Use of Laser Ablation Synthesis for the Production of Silver Nano-Antimicrobials. Antibiotics 2018, 7, 67.

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