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Antibiotics
Volume 15
Issue 6
10.3390/antibiotics15060602
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Review

Enhanced Recovery After Surgery (ERAS) and Surgical Site Infections (SSIs)

by
Marco Catarci
1,*,
Luca Pellegrino
2,
Paolo Ciano
1,
Sara Salomone
2,
Michele Benedetti
1 and
Felice Borghi
2
1
General Surgery Unit, Sandro Pertini Hospital, ASL Roma 2, Via dei Monti Tiburtini, 385, 00157 Rome, Italy
2
Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, 10060 Turin, Italy
*
Author to whom correspondence should be addressed.
Antibiotics 2026, 15(6), 602; https://doi.org/10.3390/antibiotics15060602 (registering DOI)
Submission received: 4 May 2026 / Revised: 8 June 2026 / Accepted: 9 June 2026 / Published: 12 June 2026
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Abstract

Enhanced Recovery After Surgery (ERAS®) is a multimodal perioperative framework designed to mitigate the physiological stress response to major surgery. While ERAS protocols consistently reduce length of hospital stay, overall complication rates, and healthcare costs compared to conventional care, their specific impact on surgical site infections (SSIs) remains poorly defined. This review explores the potential synergistic benefits of integrating ERAS protocols with established infection prevention bundles. By evaluating the current clinical evidence, we analyze how the co-implementation of these two evidence-based strategies can collectively reduce the incidence of SSIs.
Keywords: ERAS; surgical site infections; perioperative infections; infection prevention; perioperative care; ERAS and SSI ERAS; surgical site infections; perioperative infections; infection prevention; perioperative care; ERAS and SSI
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MDPI and ACS Style

Catarci, M.; Pellegrino, L.; Ciano, P.; Salomone, S.; Benedetti, M.; Borghi, F. Enhanced Recovery After Surgery (ERAS) and Surgical Site Infections (SSIs). Antibiotics 2026, 15, 602. https://doi.org/10.3390/antibiotics15060602

AMA Style

Catarci M, Pellegrino L, Ciano P, Salomone S, Benedetti M, Borghi F. Enhanced Recovery After Surgery (ERAS) and Surgical Site Infections (SSIs). Antibiotics. 2026; 15(6):602. https://doi.org/10.3390/antibiotics15060602

Chicago/Turabian Style

Catarci, Marco, Luca Pellegrino, Paolo Ciano, Sara Salomone, Michele Benedetti, and Felice Borghi. 2026. "Enhanced Recovery After Surgery (ERAS) and Surgical Site Infections (SSIs)" Antibiotics 15, no. 6: 602. https://doi.org/10.3390/antibiotics15060602

APA Style

Catarci, M., Pellegrino, L., Ciano, P., Salomone, S., Benedetti, M., & Borghi, F. (2026). Enhanced Recovery After Surgery (ERAS) and Surgical Site Infections (SSIs). Antibiotics, 15(6), 602. https://doi.org/10.3390/antibiotics15060602

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