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Antibiotics
Volume 11
Issue 7
10.3390/antibiotics11070839
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Review

Benefits of Combined Phage–Antibiotic Therapy for the Control of Antibiotic-Resistant Bacteria: A Literature Review

by
Kevin Diallo
1,* and
Alain Dublanchet
2
1
Department of Infective and Tropical Diseases and Internal Medicine, University Hospital of la Reunion, 97448 Saint-Pierre, France
2
2465 Rue Céline Robert, 94300 Vincennes, France
*
Author to whom correspondence should be addressed.
Antibiotics 2022, 11(7), 839; https://doi.org/10.3390/antibiotics11070839
Submission received: 30 April 2022 / Revised: 17 June 2022 / Accepted: 21 June 2022 / Published: 22 June 2022
(This article belongs to the Special Issue Antibiotics vs. Phage Therapy)
Review Reports Versions Notes

Abstract

With the increase in bacterial resistance to antibiotics, more and more therapeutic failures are being reported worldwide. The market for antibiotics is now broken due to the high cost of developing new molecules. A promising solution to bacterial resistance is combined phage–antibiotic therapy, a century-old method that can potentiate existing antibiotics by prolonging or even restoring their activity against specific bacteria. The aim of this literature review was to provide an overview of different phage–antibiotic combinations and to describe the possible mechanisms of phage–antibiotic synergy.
Keywords: phage therapy; antibiotic therapy; bacteriophage; synergy; combined activity phage therapy; antibiotic therapy; bacteriophage; synergy; combined activity

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MDPI and ACS Style

Diallo, K.; Dublanchet, A. Benefits of Combined Phage–Antibiotic Therapy for the Control of Antibiotic-Resistant Bacteria: A Literature Review. Antibiotics 2022, 11, 839. https://doi.org/10.3390/antibiotics11070839

AMA Style

Diallo K, Dublanchet A. Benefits of Combined Phage–Antibiotic Therapy for the Control of Antibiotic-Resistant Bacteria: A Literature Review. Antibiotics. 2022; 11(7):839. https://doi.org/10.3390/antibiotics11070839

Chicago/Turabian Style

Diallo, Kevin, and Alain Dublanchet. 2022. "Benefits of Combined Phage–Antibiotic Therapy for the Control of Antibiotic-Resistant Bacteria: A Literature Review" Antibiotics 11, no. 7: 839. https://doi.org/10.3390/antibiotics11070839

APA Style

Diallo, K., & Dublanchet, A. (2022). Benefits of Combined Phage–Antibiotic Therapy for the Control of Antibiotic-Resistant Bacteria: A Literature Review. Antibiotics, 11(7), 839. https://doi.org/10.3390/antibiotics11070839

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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