Therapy of Subclinical Mastitis during Lactation
Abstract
:1. Introduction
2. Results
2.1. Pretreatment Bacteriology
2.2. Bacteriological Cure
2.3. New Infection Rate
2.4. Quarter-Level Somatic Cell Count
2.5. Incidence of Clinical Mastitis within 28 Days of Enrolment
3. Discussion
3.1. Effect of Duration and Frequency of Treatment on Cure Rate
3.2. Effect of Age and SCC Duration on Cure Rate
3.3. Effect of Penicillin Resistance amongst Staph. aureus Isolates on Cure Rate
3.4. Effect of Treatment on Gland-Level SCC
4. Materials and Methods
4.1. Cow Procedures
4.2. Laboratory Techniques
4.2.1. Microbiology
4.2.2. Somatic Cell-Count Determination
4.3. Data Handling and Analysis
4.4. Power Analyses
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Control | 3 × 48 h | 5 × 24 h | 5 × 48 h | Total | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No. | % Cured | No. | % Cured | No. | % Cured | No. | % Cured | No. | % Cured | ||
Minor | NAS 1 | 13 | 0.0 | 33 | 78.8 | 37 | 83.8 | 15 | 86.7 | 98 | 71.4 |
Corynebacterium spp. | 15 | 6.7 | 36 | 58.3 | 59 | 76.3 | 9 | 100.0 | 119 | 63.9 | |
All minor | 28 | 3.6 | 69 | 68.1 | 96 | 79.2 | 24 | 91.7 | 217 | 67.3 | |
Major | Staph. aureus | 26 | 0.0 | 115 | 33.0 | 98 | 41.8 | 26 | 80.8 | 265 | 37.7 |
Strep. agalactiae | 1 | 100.0 | 1 | 100.0 | 2 | 100.0 | |||||
Strep. dysgalactiae | 6 | 16.7 | 15 | 93.3 | 11 | 90.9 | 1 | 100.0 | 33 | 78.8 | |
Strep. uberis | 8 | 0.0 | 36 | 61.1 | 42 | 59.5 | 11 | 54.5 | 97 | 54.6 | |
All Streptococci | 15 | 13.3 | 52 | 71.2 | 53 | 66.0 | 12 | 58.3 | 132 | 61.4 | |
E. coli | 2 | 100.0 | 2 | 100.0 | 4 | 100.0 | |||||
Mixed 2 | 11 | 18.2 | 33 | 33.3 | 26 | 69.2 | 9 | 88.9 | 79 | 49.4 | |
Gram -ve rods | 1 | 100.0 | 1 | 100.0 | |||||||
Nocardia spp. | 1 | 100.0 | 4 | 100.0 | 1 | 100.0 | 6 | 100.0 | |||
All majors | 52 | 7.7 | 204 | 44.1 | 183 | 54.6 | 48 | 77.1 | 480 | 46.7 | |
Total glands | 80 | 6.3 | 273 | 49.8 | 279 | 61.6 | 72 | 80.6 | 704 | 52.7 | |
Total cows | 50 | 173 | 175 | 49 |
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McDougall, S.; Clausen, L.M.; Hussein, H.M.; Compton, C.W.R. Therapy of Subclinical Mastitis during Lactation. Antibiotics 2022, 11, 209. https://doi.org/10.3390/antibiotics11020209
McDougall S, Clausen LM, Hussein HM, Compton CWR. Therapy of Subclinical Mastitis during Lactation. Antibiotics. 2022; 11(2):209. https://doi.org/10.3390/antibiotics11020209
Chicago/Turabian StyleMcDougall, Scott, Laura M. Clausen, Hassan M. Hussein, and Chris W. R. Compton. 2022. "Therapy of Subclinical Mastitis during Lactation" Antibiotics 11, no. 2: 209. https://doi.org/10.3390/antibiotics11020209
APA StyleMcDougall, S., Clausen, L. M., Hussein, H. M., & Compton, C. W. R. (2022). Therapy of Subclinical Mastitis during Lactation. Antibiotics, 11(2), 209. https://doi.org/10.3390/antibiotics11020209