The First Report of mcr-1-Carrying Escherichia coli Originating from Animals in Serbia
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Isolate ID | Phylogroup | Serotype | CH- | ST | CC | Resistance Profile | AA-Substitution | ||
---|---|---|---|---|---|---|---|---|---|
Phenotype | Genotype | GyrA | ParC | ||||||
15/2 16/2 51 | B1 | O8:H25 | CH4-32 | ST58 | CC155 | AMP, FQR, TET, COL | blaTEM-1, strA, strB, qrnS1, tet(A), mcr-1.1 | Ser83Leu | |
52 | B1 | O29:H25 | CH6-53 | ST641 | CC86 | AMP, COL | blaTEM-1, qrnS1, mcr-1.1 | ||
72/2 | A | O8:H25 | CH4-24 | ST410 | CC23 | AMP, FQR, TET, SXT, CHL, COL, | blaTEM-1, aadA1, aadA2, strA, strB, sul2, sul3, dfrA12, tet(A), tet(M), cmlA1, floR, mcr-1.1 | Ser83Leu, Asp87Asn | Ser80Ile |
Isolate ID | VAG Class | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Adherence | Secretion System | Iron Uptake | Autotransporter | TTSS Effectors | Invasion | Toxin | Antiphagocytosis | Motility | Protease | Serum Resistance | |
15/2, 16/2, 51 | cfaA, cfaB, cfaC, cfaD/cfaE, ecpA, ecpB, ecpC, ecpD, ecpE, elfA, elfC, elfD, elfG, eaeH, hcpA, hcpB, hcpC, fimA, fimC, fimD, fimE, fimF, fimG, fimH, fimI | aec15, aec16, aec17, aec18, aec19, aec22, aec23, aec24, aec25, aec26, aec27/clpV, aec28, aec29, aec30, aec31, aec32 | sitA, sitB, sitC, sitD, iroB, iroC, iroD, iroE, iroN, fyuA, irp1, irp2, ybtA, ybtE, ybtP, ybtQ, ybtS, ybtT, ybtU, ybtX | cah, ehaA, ehaB, upaG/ehaG | espL1, espL4, espR1, espX1, espX4, espX5 | ibeB, ibeC | hlyE/clyA | uge, wzc | flaA | ompT | rmlD |
52 | cfaA, cfaB, cfaC, cfaD/cfaE, ecpA, ecpB, ecpC, ecpD, ecp, elfA, elfC, elfD, elfG, eaeH, hcpA, hcpB, hcpC, fimA, fimC, fimD, fimE, fimF, fimG, fimH, fimI | ec15, aec16, aec17, aec18, aec19, aec22, aec23, aec24, aec25, aec26, aec27/clpV, aec28, aec29, aec30, aec31, aec32 | sitA, sitB, sitC, sitD, iroB, iroC, iroD, iroE, iroN, fyuA, irp1, irp2. ybtA, ybtE, ybtP, ybtQ, ybtS, ybtT, ybtU, ybtX | cah, ehaA, ehaB, upaG/ehaG | espL1, espL4, espR1, espX1, espX4, espX5 | ibeB, ibeC | hlyE/clyA | uge | flaA | rmlD | |
72/2 | cfaA, cfaB, cfaC, cfaD/cfaE, ecpA, ecpB, ecpC, ecpD, ecpE, elfC, elfD, elfG, eaeH, hcpA, hcpB, hcpC, fimA, fimC, fimD, fimE, fimF, fimG, fimH, mrkB, mrkD | aec15, aec31, fliC | agn43, upaG/ehaG | espL1, espL4, espR1, espX5 | ibeB, ibeC | hlyE/clyA |
Isolate ID | Biocide MIC Values [%] | |||
---|---|---|---|---|
Benzalkonium Chloride (BAC) | Chlorhexidine (CHX) | Isopropanol (ISO) | Glutardialdehyde (GDH) | |
51 | 0.001 | 0.00006 | 4 | 0.125 |
52 | 0.001 | 0.00003 | 6 | 0.125 |
15/2 | 0.001 | 0.00006 | 6 | 0.125 |
16/2 | 0.001 | 0.00006 | 4 | 0.125 |
72/2 | 0.002 | 0.00003 | 4 | 0.125 |
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Mišić, D.; Kiskaroly, F.; Szostak, M.P.; Cabal, A.; Ruppitsch, W.; Bernreiter-Hofer, T.; Milovanovic, V.; Feßler, A.T.; Allerberger, F.; Spergser, J.; Müller, E.; Schwarz, S.; Braun, S.D.; Monecke, S.; Ehricht, R.; Korus, M.; Benković, D.; Korzeniowska, M.; Loncaric, I. The First Report of mcr-1-Carrying Escherichia coli Originating from Animals in Serbia. Antibiotics 2021, 10, 1063. https://doi.org/10.3390/antibiotics10091063
Mišić D, Kiskaroly F, Szostak MP, Cabal A, Ruppitsch W, Bernreiter-Hofer T, Milovanovic V, Feßler AT, Allerberger F, Spergser J, Müller E, Schwarz S, Braun SD, Monecke S, Ehricht R, Korus M, Benković D, Korzeniowska M, Loncaric I. The First Report of mcr-1-Carrying Escherichia coli Originating from Animals in Serbia. Antibiotics. 2021; 10(9):1063. https://doi.org/10.3390/antibiotics10091063
Chicago/Turabian StyleMišić, Dušan, Ferenc Kiskaroly, Michael P. Szostak, Adriana Cabal, Werner Ruppitsch, Tanja Bernreiter-Hofer, Viktoria Milovanovic, Andrea T. Feßler, Franz Allerberger, Joachim Spergser, Elke Müller, Stefan Schwarz, Sascha D. Braun, Stefan Monecke, Ralf Ehricht, Maciej Korus, Damir Benković, Malgorzata Korzeniowska, and Igor Loncaric. 2021. "The First Report of mcr-1-Carrying Escherichia coli Originating from Animals in Serbia" Antibiotics 10, no. 9: 1063. https://doi.org/10.3390/antibiotics10091063