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Article

Medical-Grade Honey as an Alternative Treatment for Antibiotics in Non-Healing Wounds—A Prospective Case Series

1
Faculty of Health and Social Sciences, University of Bohemia, 370 11 České Budějovice, Czech Republic
2
DiaPodi Care spol. s r.o., 392 01 Soběslav, Czech Republic
3
Department of Health Sciences, College of Polytechnics Jihlava, 586 01 Jihlava, Czech Republic
4
Triticum Exploitatie BV, 6222 NK Maastricht, The Netherlands
5
Department of Nursing and Midwifery, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic
*
Author to whom correspondence should be addressed.
Academic Editor: Piotr Szweda
Antibiotics 2021, 10(8), 918; https://doi.org/10.3390/antibiotics10080918
Received: 25 June 2021 / Revised: 21 July 2021 / Accepted: 25 July 2021 / Published: 28 July 2021
Non-healing wounds are usually colonised by various types of bacteria. An alternative to antibiotic treatment in patients with infected wounds with local signs of inflammation may be medical-grade honey (MGH), which favourably affects the healing process with its antimicrobial, antioxidant, anti-inflammatory, and immunomodulatory properties. The objective of this study was to evaluate the effect of MGH therapy on the healing process of non-healing wounds of various aetiologies and different wound colonisations. Prospective, observation–intervention case studies (n = 9) of patients with wounds of various aetiologies (venous leg ulcers, diabetic foot ulcers, surgical wound dehiscence) are presented. All wounds were treated with MGH and the healing trajectory was rigorously and objectively monitored. In all cases, pain, odour, and exudation were quickly resolved, which led to an improvement in the quality of life of patients. Despite the proven bacterial microflora in wounds, antibiotic treatment was not necessary. The effects of MGH alleviated the signs of local infection until their complete elimination. In eight out of nine cases, the non-healing wound was completely healed. MGH has antimicrobial, anti-inflammatory, and antioxidant effects in wounds of various aetiologies and forms an effective alternative for the use of antibiotics for treating locally infected wounds. View Full-Text
Keywords: medical grade honey; antibiotic replacement; infections; wounds; objective wound assessment medical grade honey; antibiotic replacement; infections; wounds; objective wound assessment
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MDPI and ACS Style

Holubová, A.; Chlupáčová, L.; Cetlová, L.; Cremers, N.A.J.; Pokorná, A. Medical-Grade Honey as an Alternative Treatment for Antibiotics in Non-Healing Wounds—A Prospective Case Series. Antibiotics 2021, 10, 918. https://doi.org/10.3390/antibiotics10080918

AMA Style

Holubová A, Chlupáčová L, Cetlová L, Cremers NAJ, Pokorná A. Medical-Grade Honey as an Alternative Treatment for Antibiotics in Non-Healing Wounds—A Prospective Case Series. Antibiotics. 2021; 10(8):918. https://doi.org/10.3390/antibiotics10080918

Chicago/Turabian Style

Holubová, Adéla, Lucie Chlupáčová, Lada Cetlová, Niels A.J. Cremers, and Andrea Pokorná. 2021. "Medical-Grade Honey as an Alternative Treatment for Antibiotics in Non-Healing Wounds—A Prospective Case Series" Antibiotics 10, no. 8: 918. https://doi.org/10.3390/antibiotics10080918

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