Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security

Piro, Benoit; Shi, Shihui; Reisberg, Steeve; Noël, Vincent; Anquetin, Guillaume

doi:10.3390/bios6010007

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Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security

by

Benoit Piro

^*,†,

Shihui Shi

^†,

Steeve Reisberg

^†,

Vincent Noël

^† and

Guillaume Anquetin

^†

University Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, Paris 75205, France

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Biosensors 2016, 6(1), 7; https://doi.org/10.3390/bios6010007

Submission received: 22 December 2015 / Revised: 16 February 2016 / Accepted: 19 February 2016 / Published: 29 February 2016

(This article belongs to the Special Issue Affinity Sensors)

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Abstract

We review here the most frequently reported targets among the electrochemical immunosensors and aptasensors: antibiotics, bisphenol A, cocaine, ochratoxin A and estradiol. In each case, the immobilization procedures are described as well as the transduction schemes and the limits of detection. It is shown that limits of detections are generally two to three orders of magnitude lower for immunosensors than for aptasensors, due to the highest affinities of antibodies. No significant progresses have been made to improve these affinities, but transduction schemes were improved instead, which lead to a regular improvement of the limit of detections corresponding to ca. five orders of magnitude over these last 10 years. These progresses depend on the target, however.

Keywords: immunosensor; aptasensor; ciprofloxacin; enrofloxacin; ofloxacin; tetracyclines; neomycin; tobramycin; ampicillin; kanamycin; sulfonamides; bisphenol A; cocaine; ochratoxin A; estradiol

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MDPI and ACS Style

Piro, B.; Shi, S.; Reisberg, S.; Noël, V.; Anquetin, G. Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security. Biosensors 2016, 6, 7. https://doi.org/10.3390/bios6010007

AMA Style

Piro B, Shi S, Reisberg S, Noël V, Anquetin G. Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security. Biosensors. 2016; 6(1):7. https://doi.org/10.3390/bios6010007

Chicago/Turabian Style

Piro, Benoit, Shihui Shi, Steeve Reisberg, Vincent Noël, and Guillaume Anquetin. 2016. "Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security" Biosensors 6, no. 1: 7. https://doi.org/10.3390/bios6010007

APA Style

Piro, B., Shi, S., Reisberg, S., Noël, V., & Anquetin, G. (2016). Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security. Biosensors, 6(1), 7. https://doi.org/10.3390/bios6010007

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security

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