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Biosensors
Volume 13
Issue 6
10.3390/bios13060598
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Review

Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End

by
Miao Liu
†,
Junyang Li
† and
Cherie S. Tan
*
Medical College, Tianjin University, Tianjin 300072, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Biosensors 2023, 13(6), 598; https://doi.org/10.3390/bios13060598
Submission received: 21 April 2023 / Revised: 24 May 2023 / Accepted: 29 May 2023 / Published: 31 May 2023
(This article belongs to the Section Biosensors and Healthcare)
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Abstract

The biomedical field has always fostered innovation and the development of various new technologies. Beginning in the last century, demand for picoampere-level current detection in biomedicine has increased, leading to continuous breakthroughs in biosensor technology. Among emerging biomedical sensing technologies, nanopore sensing has shown great potential. This paper reviews nanopore sensing applications, such as chiral molecules, DNA sequencing, and protein sequencing. However, the ionic current for different molecules differs significantly, and the detection bandwidths vary as well. Therefore, this article focuses on current sensing circuits, and introduces the latest design schemes and circuit structures of different feedback components of transimpedance amplifiers mainly used in nanopore DNA sequencing.
Keywords: nanopores; biosensors; DNA sequencing; protein sequencing; chiral molecules; transimpedance amplifiers nanopores; biosensors; DNA sequencing; protein sequencing; chiral molecules; transimpedance amplifiers

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MDPI and ACS Style

Liu, M.; Li, J.; Tan, C.S. Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End. Biosensors 2023, 13, 598. https://doi.org/10.3390/bios13060598

AMA Style

Liu M, Li J, Tan CS. Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End. Biosensors. 2023; 13(6):598. https://doi.org/10.3390/bios13060598

Chicago/Turabian Style

Liu, Miao, Junyang Li, and Cherie S. Tan. 2023. "Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End" Biosensors 13, no. 6: 598. https://doi.org/10.3390/bios13060598

APA Style

Liu, M., Li, J., & Tan, C. S. (2023). Unlocking the Power of Nanopores: Recent Advances in Biosensing Applications and Analog Front-End. Biosensors, 13(6), 598. https://doi.org/10.3390/bios13060598

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