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Article

Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field

Department of Biomedical Engineering, School of Basic Medical Science, Central South University, Changsha 410017, China
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Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Biosensors 2022, 12(7), 463; https://doi.org/10.3390/bios12070463
Received: 25 May 2022 / Revised: 18 June 2022 / Accepted: 22 June 2022 / Published: 27 June 2022
(This article belongs to the Special Issue Activatable Probes for Biosensing, Imaging, and Photomedicine)
This paper aims to propose a new photoacoustic/ultrasound endoscopic imaging reconstruction algorithm based on the approximate Gaussian acoustic field which significantly improves the resolution and signal-to-noise ratio (SNR) of the out-of-focus region. We demonstrated the method by numerical calculations and investigated the applicability of the algorithm in a chicken breast phantom. The validation was finally performed by the rabbit rectal endoscopy experiment. Simulation results show that the lateral resolution of the target point in the out-of-focus region can be well optimized with this new algorithm. Phantom experimental results show that the lateral resolution of the indocyanine green (ICG) tube in the photoacoustic image is reduced from 3.975 mm to 1.857 mm by using our new algorithm, which is a 52.3% improvement. Ultrasound images also show a significant improvement in lateral resolution. The results of the rabbit rectal endoscopy experiment prove that the algorithm we proposed is capable of providing higher-quality photoacoustic/ultrasound images. In conclusion, the algorithm enables fast acoustic resolution photoacoustic/ ultrasonic dynamic focusing and effectively improves the imaging quality of the system, which has significant guidance for the design of acoustic resolution photoacoustic/ultrasound endoscopy systems. View Full-Text
Keywords: photoacoustic endoscopy; Gaussian acoustic field; dynamic focusing photoacoustic endoscopy; Gaussian acoustic field; dynamic focusing
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MDPI and ACS Style

Wang, Y.; Yuan, C.; Jiang, J.; Peng, K.; Wang, B. Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field. Biosensors 2022, 12, 463. https://doi.org/10.3390/bios12070463

AMA Style

Wang Y, Yuan C, Jiang J, Peng K, Wang B. Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field. Biosensors. 2022; 12(7):463. https://doi.org/10.3390/bios12070463

Chicago/Turabian Style

Wang, Yongjun, Chuqi Yuan, Jinsheng Jiang, Kuan Peng, and Bo Wang. 2022. "Photoacoustic/Ultrasound Endoscopic Imaging Reconstruction Algorithm Based on the Approximate Gaussian Acoustic Field" Biosensors 12, no. 7: 463. https://doi.org/10.3390/bios12070463

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