Conducting Polymer-Infused Electrospun Fibre Mat Modified by POEGMA Brushes as Antifouling Biointerface
Abstract
:1. Introduction
2. Materials and Methods
2.1. Synthesis of (3,4-Ethylenedioxythiophene) Methyl 2-Bromopropanoate (EDOTBr)
2.2. Sulfonation of Polystyrene-Block-Poly(Ethylene-Ran-Butylene)-Block-Polystyrene (SEBS)
2.3. Fabrication of Electrospun Fibre Mats
2.4. Chemical Oxidative Polymerisation of EDOT on the Electrospun Fibre Mats
2.5. Electropolymerisation of P(EDOT-co-EDOTBr) on the sSEBS-PEDOT Fibre Mats
2.6. Grafting POEGMA Brushes on the sSEBS-PEDOT/P(EDOT-EDOTBr) Fibre Mat
2.7. Protein Adsorption Test
2.8. Cell Viability and Proliferation
2.9. Scanning Electron Microscopy (SEM)
2.10. Four-Point Probe Conductivity Meter
2.11. Raman Spectroscopy
2.12. X-ray Photoelectron Spectroscopy (XPS)
2.13. 1H NMR Measurement
2.14. Water Contact Angle Measurement
3. Results and Discussion
3.1. Fabrication of POEGMA Brush Grafted Electrospun Fibre Mat
3.2. Characterization of Electrospun Conducting sSEBS-PEDOT Fibre Mat
3.3. Electrochemical Copolymerisation of P(EDOT-co-EDOTBr) on sSEBS-PEDOT Fibre Mat
3.4. Grafting POEGMA Brushes from sSEBS-PEDOT/P(EDOT-co-EDOTBr) Fibre Mat
3.5. Antifouling Properties of sSEBS-PEDOT/P(EDOT-co-EDOTBr)-g-POEGMA Fibre Mat
3.6. Cell Viability and Proliferation Assessment Using PrestoBlueTM
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Ashraf, J.; Lau, S.; Akbarinejad, A.; Evans, C.W.; Williams, D.E.; Barker, D.; Travas-Sejdic, J. Conducting Polymer-Infused Electrospun Fibre Mat Modified by POEGMA Brushes as Antifouling Biointerface. Biosensors 2022, 12, 1143. https://doi.org/10.3390/bios12121143
Ashraf J, Lau S, Akbarinejad A, Evans CW, Williams DE, Barker D, Travas-Sejdic J. Conducting Polymer-Infused Electrospun Fibre Mat Modified by POEGMA Brushes as Antifouling Biointerface. Biosensors. 2022; 12(12):1143. https://doi.org/10.3390/bios12121143
Chicago/Turabian StyleAshraf, Jesna, Sandy Lau, Alireza Akbarinejad, Clive W. Evans, David E. Williams, David Barker, and Jadranka Travas-Sejdic. 2022. "Conducting Polymer-Infused Electrospun Fibre Mat Modified by POEGMA Brushes as Antifouling Biointerface" Biosensors 12, no. 12: 1143. https://doi.org/10.3390/bios12121143