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Open AccessArticle

Surface Characteristics and Biological Evaluation of Si-DLC Coatings Fabricated Using Magnetron Sputtering Method on Ti6Al7Nb Substrate

1
Faculty of Mechanical Engineering, Institute of Materials Science and Engineering, Lodz University of Technology, 1/15 Stefanowskiego St., 90-924 Lodz, Poland
2
Bionanopark Ltd., Molecular and Nanostructural Biophysics Laboratory, 114/116 Dubois St., 93-465 Lodz, Poland
3
Faculty of Process and Environmental Engineering, Department of Molecular Engineering, Lodz University of Technology, 213 Wolczanska St., 90-924 Lodz, Poland
*
Author to whom correspondence should be addressed.
Nanomaterials 2019, 9(6), 812; https://doi.org/10.3390/nano9060812
Received: 4 May 2019 / Revised: 21 May 2019 / Accepted: 27 May 2019 / Published: 29 May 2019
(This article belongs to the Special Issue Synthesis and Modification of Nanostructured Thin Films)
Diamond-like carbon (DLC) coatings are well known as protective coatings for biomedical applications. Furthermore, the incorporation of different elements, such as silicon (Si), in the carbon matrix changes the bio-functionality of the DLC coatings. This has also been proven by the results obtained in this work. The Si-DLC coatings were deposited on the Ti6Al7Nb alloy, which is commonly used in clinical practice, using the magnetron sputtering method. According to the X-ray photoelectron spectroscopy (XPS) analysis, the content of silicon in the examined coatings varied from ~2 at.% up to ~22 at.%. Since the surface characteristics are key factors influencing the cell response, the results of the cells’ proliferation and viability assays (live/dead and XTT (colorimetric assays using tetrazolium salt)) were correlated with the surface properties. The surface free energy (SFE) measurements, Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS) analysis demonstrated that the polarity and wettability of the surfaces examined increase with increasing Si concentration, and therefore the adhesion and proliferation of cells was enhanced. The results obtained revealed that the biocompatibility of Si-doped DLC coatings, regardless of the Si content, remains at a very high level (the observed viability of endothelial cells is above 70%). View Full-Text
Keywords: DLC bio-functionality; silicon doping; diffusion barrier; biocompatibility; proliferation improvement; endothelial cells DLC bio-functionality; silicon doping; diffusion barrier; biocompatibility; proliferation improvement; endothelial cells
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MDPI and ACS Style

Bociaga, D.; Sobczyk-Guzenda, A.; Komorowski, P.; Balcerzak, J.; Jastrzebski, K.; Przybyszewska, K.; Kaczmarek, A. Surface Characteristics and Biological Evaluation of Si-DLC Coatings Fabricated Using Magnetron Sputtering Method on Ti6Al7Nb Substrate. Nanomaterials 2019, 9, 812.

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