Next Article in Journal
Synthesis and Morphology Control of Nanoporous Cu2O/Cu and Their Application as Electrode Materials for Capacitors
Next Article in Special Issue
Photoelectrocatalytic Hydrogen Generation Enabled by CdS Passivated ZnCuInSe Quantum Dot-Sensitized TiO2 Decorated with Ag Nanoparticles
Previous Article in Journal
Photocatalytic Decomposition of Gaseous HCHO over Ag Modified TiO2 Nanosheets at Ambient Temperature
Previous Article in Special Issue
A Novel Fluorescence and SPE Adsorption Nanomaterials of Molecularly Imprinted Polymers Based on Quantum Dot-Grafted Covalent Organic Frameworks for the High Selectivity and Sensitivity Detection of Ferulic Acid
Open AccessCommunication

DNA-Based Assembly of Quantum Dots into Dimers and Helices

by Tao Zhang *,† and Tim Liedl
Faculty of Physics and Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität München (LMU), D-80539 Munich, Germany
*
Author to whom correspondence should be addressed.
Current address: Max-Planck-Institute for Intelligent Systems, D-70569 Stuttgart, Germany.
Nanomaterials 2019, 9(3), 339; https://doi.org/10.3390/nano9030339
Received: 30 January 2019 / Revised: 20 February 2019 / Accepted: 21 February 2019 / Published: 2 March 2019
(This article belongs to the Special Issue Applications of Quantum Dots)
Owing to their unique optical properties, colloidal quantum dots (QDs) have attracted much attention as versatile fluorescent markers with broad biological and physical applications. On the other hand, DNA-based assembly has proven to be a powerful bottom-up approach to create designer nanoscale objects and to use these objects for the site-directed arrangement of guest components. To achieve good colloidal stability and accurate positioning of QDs on DNA templates, robust QD surface functionalization is crucial. Here, we present a simple and reliable conjugation method for the direct attachment of DNA molecules to QDs. Phosphorothiolated regions of chimera oligonucleotides are attached and incorporated into a ZnS layer freshly growing in situ on QDs that were rendered water soluble with hydrophilic ligands in a prior step. The reaction can be completed in a 2 mL plastic tube without any special equipment. The utility of these DNA-labeled QDs is demonstrated via prototypical assemblies such as QDs dimers with various spacings and chiral helical architectures. View Full-Text
Keywords: quantum dots; DNA–QDs conjugation; DNA nanotechnology quantum dots; DNA–QDs conjugation; DNA nanotechnology
Show Figures

Graphical abstract

MDPI and ACS Style

Zhang, T.; Liedl, T. DNA-Based Assembly of Quantum Dots into Dimers and Helices. Nanomaterials 2019, 9, 339.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop