Next Article in Journal
Bare Iron Oxide Nanoparticles for Magnetic Harvesting of Microalgae: From Interaction Behavior to Process Realization
Next Article in Special Issue
Carbon-Based Fe3O4 Nanocomposites Derived from Waste Pomelo Peels for Magnetic Solid-Phase Extraction of 11 Triazole Fungicides in Fruit Samples
Previous Article in Journal
Biofunctionalized Lysophosphatidic Acid/Silk Fibroin Film for Cornea Endothelial Cell Regeneration
Previous Article in Special Issue
Magnesium and Nitrogen Co-Doped Mesoporous Carbon with Enhanced Microporosity for CO2 Adsorption
Open AccessArticle

Antimicrobial Activity of New Materials Based on Lavender and Basil Essential Oils and Hydroxyapatite

1
National Institute of Materials Physics, 405 A Atomistilor Street, P.O. Box MG7, 077125 Magurele, Romania
2
HORIBA Jobin Yvon S.A.S., 6-18, Rue du Canal, 91165 Longjumeau CEDEX, France
3
University of Agronomic Sciences and Veterinary Medicine, Faculty of Horticulture, 59 Mărăşti Blvd., 011464 Bucharest, Romania
4
Microbiology Department, Faculty of Biology, University of Bucharest, 1–3 Portocalelor Lane, 77206 Bucharest, Romania
5
Earth, Environmental and Life Sciences Section, Research Institute of the University of Bucharest (ICUB), 91-95 Splaiul Independentei, 050095 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Nanomaterials 2018, 8(5), 291; https://doi.org/10.3390/nano8050291
Received: 28 March 2018 / Revised: 25 April 2018 / Accepted: 26 April 2018 / Published: 30 April 2018
(This article belongs to the Special Issue Preparation and Application of Hybrid Nanomaterials)
This study presents, for the first-time, the results of a study on the hydrodynamic diameter of essential oils (EOs) of basil and lavender in water, and solutions of EOs of basil (B) and lavender (L) and hydroxyapatite (HAp). The possible influence of basil and lavender EOs on the size of hydroxyapatite nanoparticles was analyzed by Scanning Electron Microscopy (SEM). We also investigated the in vitro antimicrobial activity of plant EOs and plant EOs hydroxyapatite respectively, against Gram-positive bacteria (methicillin-resistant Staphylococcus aureus1144 (MRSA 1144) and S. aureus 1426) and Gram-negative bacteria (Escherichia coli ATCC 25922 and Escherichia coli ESBL 4493). From the autocorrelation function, obtained by Dynamic Light Scattering (DLS) measurements it was observed that basil yielded one peak at an average hydrodynamic diameter of 354.16 nm, while lavender yielded one peak at an average hydrodynamic diameter of 259.76 nm. In the case of HAp nanoparticles coated with basil (HApB) and lavender (HApL) essential oil, the aggregation was minimal. We found that the lavender EO exhibited a very good inhibitory growth activity (MIC values ranging from <0.1% for E. coli reference strain to 0.78% for S. aureus strains). The biological studies indicated that HapL material displayed an enhanced antimicrobial activity, indicating the potential use of HAp as vehicle for low concentrations of lavender EO with antibacterial properties. Flow cytometry analysis (FCM) allowed us to determine some of the potential mechanisms of the antimicrobial activities of EOs, suggesting that lavender EO was active against E. coli by interfering with membrane potential, the membrane depolarization effect being increased by incorporation of the EOs into the microporous structure of HAp. These findings could contribute to the development of new antimicrobial agents that are urgently needed for combating the antibiotic resistance phenomena. View Full-Text
Keywords: hydroxyapatite; essential oil; Dynamic Light Scattering (DLS); antimicrobial studies hydroxyapatite; essential oil; Dynamic Light Scattering (DLS); antimicrobial studies
Show Figures

Figure 1

MDPI and ACS Style

Predoi, D.; Iconaru, S.L.; Buton, N.; Badea, M.L.; Marutescu, L. Antimicrobial Activity of New Materials Based on Lavender and Basil Essential Oils and Hydroxyapatite. Nanomaterials 2018, 8, 291.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop