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Open AccessArticle

The DaNa2.0 Knowledge Base Nanomaterials—An Important Measure Accompanying Nanomaterials Development

NanoCASE GmbH, St. Gallerstr. 58, 9032 Engelburg, Switzerland
Society for Chemical Engineering and Biotechnology (DECHEMA), Theodor-Heuss-Allee 25, 60486 Frankfurt am Main, Germany
Department Bioanalytical Ecotoxicology (BIOTOX), Helmholtz Centre for Environmental Research GmbH—UFZ, Permoserstraße 15, 04318 Leipzig, Germany
Institute for Automation and Applied Informatics (IAI), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
Author to whom correspondence should be addressed.
Nanomaterials 2018, 8(4), 204;
Received: 5 March 2018 / Revised: 27 March 2018 / Accepted: 27 March 2018 / Published: 29 March 2018
(This article belongs to the Special Issue Nanosafety 2017)
Nanotechnology is closely related to the tailored manufacturing of nanomaterials for a huge variety of applications. However, such applications with newly developed materials are also a reason for concern. The DaNa2.0 project provides information and support for these issues on the web in condensed and easy-to-understand wording. Thus, a key challenge in the field of advanced materials safety research is access to correct and reliable studies and validated results. For nanomaterials, there is currently a continuously increasing amount of publications on toxicological issues, but criteria to evaluate the quality of these studies are necessary to use them e.g., for regulatory purposes. DaNa2.0 discusses scientific results regarding 26 nanomaterials based on actual literature that has been selected after careful evaluation following a literature criteria checklist. This checklist is publicly available, along with a selection of standardized operating protocols (SOPs) established by different projects. The spectrum of information is rounded off by further articles concerning basics or crosscutting topics in nanosafety research. This article is intended to give an overview on DaNa2.0 activities to support reliable toxicity testing and science communication alike. View Full-Text
Keywords: nanomaterials; nanotoxicology; safety; basic information; literature criteria checklist nanomaterials; nanotoxicology; safety; basic information; literature criteria checklist
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Krug, H.F.; Bohmer, N.; Kühnel, D.; Marquardt, C.; Nau, K.; Steinbach, C. The DaNa2.0 Knowledge Base Nanomaterials—An Important Measure Accompanying Nanomaterials Development. Nanomaterials 2018, 8, 204.

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