Multifunctional Hybrid MoS2-PEGylated/Au Nanostructures with Potential Theranostic Applications in Biomedicine
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.1.1. Reagents
2.1.2. Cell Lines and Reagents
2.2. Methods
2.2.1. MoS2-PEG Synthesis
2.2.2. Au Nanoparticles Production
2.2.3. MoS2-PEG/Au Synthesis
2.2.4. Sample Preparation for Electrical Measurements
2.2.5. Cellular Viability Based on Resazurin Reduction Assay
2.2.6. Hoechst Nuclear Staining Assay
2.2.7. Characterization
3. Results and Discussion
Characterization of Flower-Like MoS2-PEG/Au
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Samples | ||
---|---|---|
Electrical Parameters | MoS2-PEG | MoS2-PEG/Au |
Sheet resistance (kΩ sq−1) | 671.4 | 218.1 |
Resistivity (Ω m) | 1342.7 | 436.2 |
Conductivity (10−6 S cm−1) | 7.4 | 22.9 |
Materials | Contact Angle (°) |
---|---|
Graphite (substrate) | 58.1 ± 3.9 |
MoS2-PEG | 30.7 ± 3.4 |
MoS2-PEG/Au | 37.1 ± 2.1 |
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Malagrino, T.R.S.; Godoy, A.P.; Barbosa, J.M.; Lima, A.G.T.; Sousa, N.C.O.; Pedrotti, J.J.; Garcia, P.S.; Paniago, R.M.; Andrade, L.M.; Domingues, S.H.; et al. Multifunctional Hybrid MoS2-PEGylated/Au Nanostructures with Potential Theranostic Applications in Biomedicine. Nanomaterials 2022, 12, 2053. https://doi.org/10.3390/nano12122053
Malagrino TRS, Godoy AP, Barbosa JM, Lima AGT, Sousa NCO, Pedrotti JJ, Garcia PS, Paniago RM, Andrade LM, Domingues SH, et al. Multifunctional Hybrid MoS2-PEGylated/Au Nanostructures with Potential Theranostic Applications in Biomedicine. Nanomaterials. 2022; 12(12):2053. https://doi.org/10.3390/nano12122053
Chicago/Turabian StyleMalagrino, Thiago R. S., Anna P. Godoy, Juliano M. Barbosa, Abner G. T. Lima, Nei C. O. Sousa, Jairo J. Pedrotti, Pamela S. Garcia, Roberto M. Paniago, Lídia M. Andrade, Sergio H. Domingues, and et al. 2022. "Multifunctional Hybrid MoS2-PEGylated/Au Nanostructures with Potential Theranostic Applications in Biomedicine" Nanomaterials 12, no. 12: 2053. https://doi.org/10.3390/nano12122053