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Article

Rapid Preparation of Fluorescent Carbon Dots from Pine Needles for Chemical Analysis

1
Department of Medical Applied Chemistry, Chung Shan Medical University, Taichung 402, Taiwan
2
Department of Medical Education, Chung Shan Medical University Hospital, Taichung 402, Taiwan
3
Department of Applied Chemistry, National Chi Nan University, Puli, Nantou 545, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editors: Constantine D. Stalikas and Hideya Kawasaki
Nanomaterials 2022, 12(1), 66; https://doi.org/10.3390/nano12010066
Received: 26 November 2021 / Revised: 23 December 2021 / Accepted: 25 December 2021 / Published: 28 December 2021
Fluorescent carbon dots with blue, green, and red emissions were rapidly prepared from modified pine needles through microwave irradiation in a one-pot reaction. The fluorescence intensity and emission versatility for a carbon source were experimentally optimized. The reaction times were under 10 min and the reaction temperatures were lower than 220 °C. Potential applications of magnetic fluorescence-linked immunoassays of carcinoembryonic antigen (CEA) and tumor necrosis factor-alpha (TNF-α) were presented. The detection limits for CEA and TNF-α (3.1 and 2.8 pg mL−1, respectively) are lower than those presented in other reports, whereas the linear ranges for CEA and TNF-α (9 pg mL−1 to 18 ng mL−1 and 8.5 pg mL−1 to 17 ng mL−1, respectively) are wider than those presented in other reports. Magnetic immunoassays with fluorescent CDs prepared from pine needles can enable rapid, sensitive, and selective detections for biochemical analysis. View Full-Text
Keywords: carbon dots; pine needles; chemical analysis; carcinoembryonic antigen; tumor necrosis factor-alpha carbon dots; pine needles; chemical analysis; carcinoembryonic antigen; tumor necrosis factor-alpha
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MDPI and ACS Style

Tsai, H.; Chang, K.; Lee, W.; Fuh, C.B. Rapid Preparation of Fluorescent Carbon Dots from Pine Needles for Chemical Analysis. Nanomaterials 2022, 12, 66. https://doi.org/10.3390/nano12010066

AMA Style

Tsai H, Chang K, Lee W, Fuh CB. Rapid Preparation of Fluorescent Carbon Dots from Pine Needles for Chemical Analysis. Nanomaterials. 2022; 12(1):66. https://doi.org/10.3390/nano12010066

Chicago/Turabian Style

Tsai, Hweiyan, Kaiying Chang, Wanshing Lee, and C. B. Fuh. 2022. "Rapid Preparation of Fluorescent Carbon Dots from Pine Needles for Chemical Analysis" Nanomaterials 12, no. 1: 66. https://doi.org/10.3390/nano12010066

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