Next Article in Journal
Gallic Acid Based Black Tea Extract as a Stabilizing Agent in ZnO Particles Green Synthesis
Previous Article in Journal
Catalytic Dehydration of Fructose to 5-Hydroxymethylfurfural in Aqueous Medium over Nb2O5-Based Catalysts
Previous Article in Special Issue
Targeting NF-κB with Nanotherapy in a Mouse Model of Adult T-Cell Leukemia/Lymphoma
Article

Copper-Silver Nanohybrids: SARS-CoV-2 Inhibitory Surfaces

1
Department of Virology, Faculty of Medicine, University of Helsinki, P.O. Box 21, 00014 Helsinki, Finland
2
Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014 Helsinki, Finland
3
VTT Technical Research Center of Finland Ltd., P.O. Box 1000, 02044 Espoo, Finland
*
Authors to whom correspondence should be addressed.
Academic Editor: Eleonore Fröhlich
Nanomaterials 2021, 11(7), 1820; https://doi.org/10.3390/nano11071820
Received: 18 June 2021 / Revised: 9 July 2021 / Accepted: 10 July 2021 / Published: 13 July 2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a severe health threat. The COVID-19 infections occurring in humans and animals render human-animal interfaces hot spots for spreading the pandemic. Lessons from the past point towards the antiviral properties of copper formulations; however, data showing the “contact-time limit” surface inhibitory efficacy of copper formulations to contain SARS-CoV-2 are limited. Here, we show the rapid inhibition of SARS-CoV-2 after only 1 and 5 min on two different surfaces containing copper-silver (Cu-Ag) nanohybrids. We characterized the nanohybrids’ powder and surfaces using a series of sophisticated microscopy tools, including transmission and scanning electron microscopes (TEM and SEM) and energy-dispersive X-ray spectroscopy (EDX). We used culturing methods to demonstrate that Cu-Ag nanohybrids with high amounts of Cu (~65 and 78 wt%) and lower amounts of Ag (~7 and 9 wt%) inhibited SARS-CoV-2 efficiently. Collectively, the present work reveals the rapid SARS-CoV-2 surface inhibition and the promising application of such surfaces to break the SARS-CoV-2 transmission chain. For example, such applications could be invaluable within a hospital or live-stock settings, or any public place with surfaces that people frequently touch (i.e., public transportation, shopping malls, elevators, and door handles) after the precise control of different parameters and toxicity evaluations. View Full-Text
Keywords: SARS-CoV-2; human-animal interfaces; nanohybrids; copper; silver; inhibitory surfaces SARS-CoV-2; human-animal interfaces; nanohybrids; copper; silver; inhibitory surfaces
Show Figures

Figure 1

MDPI and ACS Style

Mosselhy, D.A.; Kareinen, L.; Kivistö, I.; Aaltonen, K.; Virtanen, J.; Ge, Y.; Sironen, T. Copper-Silver Nanohybrids: SARS-CoV-2 Inhibitory Surfaces. Nanomaterials 2021, 11, 1820. https://doi.org/10.3390/nano11071820

AMA Style

Mosselhy DA, Kareinen L, Kivistö I, Aaltonen K, Virtanen J, Ge Y, Sironen T. Copper-Silver Nanohybrids: SARS-CoV-2 Inhibitory Surfaces. Nanomaterials. 2021; 11(7):1820. https://doi.org/10.3390/nano11071820

Chicago/Turabian Style

Mosselhy, Dina A., Lauri Kareinen, Ilkka Kivistö, Kirsi Aaltonen, Jenni Virtanen, Yanling Ge, and Tarja Sironen. 2021. "Copper-Silver Nanohybrids: SARS-CoV-2 Inhibitory Surfaces" Nanomaterials 11, no. 7: 1820. https://doi.org/10.3390/nano11071820

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop