Next Article in Journal
Defects and Strain Engineering of Structural, Elastic, and Electronic Properties of Boron-Phosphide Monolayer: A Hybrid Density Functional Theory Study
Next Article in Special Issue
DFT and TD-DFT Investigation of a Charge Transfer Surface Resonance Raman Model of N3 Dye Bound to a Small TiO2 Nanoparticle
Previous Article in Journal
Diamond Nanoparticles-Porphyrin mTHPP Conjugate as Photosensitizing Platform: Cytotoxicity and Antibacterial Activity
Previous Article in Special Issue
Charge-Transfer Induced by the Oxygen Vacancy Defects in the Ag/MoO3 Composite System
 
 
Article

SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2

1
Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia
2
Department of Microbiology, Virology and Immunology, I.M. Sechenov First Moscow State Medical University, 125009 Moscow, Russia
3
Institute of Solid State Physics of Russian Academy of Science, 142432 Chernogolovka, Russia
4
National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia
5
Institute of Physiologically Active Compounds of Russian Academy of Science, 142432 Chernogolovka, Russia
6
Belozersky Research Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia
7
Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products RAS, 108819 Moscow, Russia
*
Authors to whom correspondence should be addressed.
Academic Editors: Ronald Birke and Bing Zhao
Nanomaterials 2021, 11(6), 1394; https://doi.org/10.3390/nano11061394
Received: 30 April 2021 / Revised: 21 May 2021 / Accepted: 22 May 2021 / Published: 25 May 2021
(This article belongs to the Special Issue Application of SERS for Nanomaterials)
During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses. View Full-Text
Keywords: SARS-CoV-2; COVID-19; SERS; silver colloids; aptamer; optical sensor; respiratory viral infections SARS-CoV-2; COVID-19; SERS; silver colloids; aptamer; optical sensor; respiratory viral infections
Show Figures

Figure 1

MDPI and ACS Style

Zavyalova, E.; Ambartsumyan, O.; Zhdanov, G.; Gribanyov, D.; Gushchin, V.; Tkachuk, A.; Rudakova, E.; Nikiforova, M.; Kuznetsova, N.; Popova, L.; Verdiev, B.; Alatyrev, A.; Burtseva, E.; Ignatieva, A.; Iliukhina, A.; Dolzhikova, I.; Arutyunyan, A.; Gambaryan, A.; Kukushkin, V. SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2. Nanomaterials 2021, 11, 1394. https://doi.org/10.3390/nano11061394

AMA Style

Zavyalova E, Ambartsumyan O, Zhdanov G, Gribanyov D, Gushchin V, Tkachuk A, Rudakova E, Nikiforova M, Kuznetsova N, Popova L, Verdiev B, Alatyrev A, Burtseva E, Ignatieva A, Iliukhina A, Dolzhikova I, Arutyunyan A, Gambaryan A, Kukushkin V. SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2. Nanomaterials. 2021; 11(6):1394. https://doi.org/10.3390/nano11061394

Chicago/Turabian Style

Zavyalova, Elena, Oganes Ambartsumyan, Gleb Zhdanov, Dmitry Gribanyov, Vladimir Gushchin, Artem Tkachuk, Elena Rudakova, Maria Nikiforova, Nadezhda Kuznetsova, Liubov Popova, Bakhtiyar Verdiev, Artem Alatyrev, Elena Burtseva, Anna Ignatieva, Anna Iliukhina, Inna Dolzhikova, Alexander Arutyunyan, Alexandra Gambaryan, and Vladimir Kukushkin. 2021. "SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2" Nanomaterials 11, no. 6: 1394. https://doi.org/10.3390/nano11061394

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop