Next Article in Journal
Scalable Preparation of Low-Defect Graphene by Urea-Assisted Liquid-Phase Shear Exfoliation of Graphite and Its Application in Doxorubicin Analysis
Previous Article in Journal
Continuous Carbonation for Synthesis of Pseudo-Boehmite by using Cross-Flow Rotating Packed Bed through the Reaction of NaAlO2 Solution with CO2 Gas
Previous Article in Special Issue
Comparative in Vitro Cytotoxicity of Realistic Doses of Benchmark Multi-Walled Carbon Nanotubes towards Macrophages and Airway Epithelial Cells
Open AccessReview

Biocompatibility and Carcinogenicity of Carbon Nanotubes as Biomaterials

by Kaoru Aoki 1 and Naoto Saito 2,*
1
Physical Therapy Division, School of Health Sciences, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
2
Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
*
Author to whom correspondence should be addressed.
Nanomaterials 2020, 10(2), 264; https://doi.org/10.3390/nano10020264
Received: 14 January 2020 / Accepted: 31 January 2020 / Published: 4 February 2020
(This article belongs to the Special Issue Toxicology of Carbon Nanomaterials)
With the development of nanotechnology in recent years, there have been concerns about the health effects of nanoparticles. Carbon nanotubes (CNTs) are fibrous nanoparticles with a micro-sized length and nano-sized diameter, which exhibit excellent physical properties and are widely studied for their potential application in medicine. However, asbestos has been historically shown to cause pleural malignant mesothelioma and lung cancer by inhalation exposure. Because carbon nanotubes are also fibrous nanotubes, some have raised concerns about its possible carcinogenicity. We have reported that there is no clear evidence of carcinogenicity by local and intravenous administration of multi-walled CNTs to cancer mice models. We firmly believe that CNTs can be a safe, new, and high-performance biomaterials by controlling its type, site of administration, and dosage. View Full-Text
Keywords: carbon nanotubes; biocompatibility; carcinogenicity carbon nanotubes; biocompatibility; carcinogenicity
Show Figures

Figure 1

MDPI and ACS Style

Aoki, K.; Saito, N. Biocompatibility and Carcinogenicity of Carbon Nanotubes as Biomaterials. Nanomaterials 2020, 10, 264.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop