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Review

From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior

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Department of Mechanical and Manufacturing Engineering, University of Cyprus, 75 Kallipoleos Avenue, P.O. Box 20537, Nicosia 1678, Cyprus
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Laboratory of Magnetic Fluids, Center for Fundamental and Advanced Technical Research, Romanian Academy–Timisoara Branch, Mihai Viteazul Ave. 24, 300223 Timisoara, Romania
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Department for Neutron Materials Characterization, Institute for Energy Technology (IFE), 2027 Kjeller, Norway
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Soós Ernő Water Technology Research and Development Center, University of Pannonia, Zrínyi M. Str. 18., H-8800 Nagykanizsa, Hungary
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Department of Physics of Nanostructured Systems, National Institute for Research and Development of Isotopic and Molecular Technologies, Donat Str. 67-103, 400293 Cluj-Napoca, Romania
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Authors to whom correspondence should be addressed.
Nanomaterials 2020, 10(11), 2178; https://doi.org/10.3390/nano10112178
Received: 19 September 2020 / Revised: 19 October 2020 / Accepted: 20 October 2020 / Published: 31 October 2020
(This article belongs to the Special Issue Multicore Magnetic Nanoparticles for Biomedical Applications)
Iron oxide nanoparticles are the basic components of the most promising magnetoresponsive nanoparticle systems for medical (diagnosis and therapy) and bio-related applications. Multi-core iron oxide nanoparticles with a high magnetic moment and well-defined size, shape, and functional coating are designed to fulfill the specific requirements of various biomedical applications, such as contrast agents, heating mediators, drug targeting, or magnetic bioseparation. This review article summarizes recent results in manufacturing multi-core magnetic nanoparticle (MNP) systems emphasizing the synthesis procedures, starting from ferrofluids (with single-core MNPs) as primary materials in various assembly methods to obtain multi-core magnetic particles. The synthesis and functionalization will be followed by the results of advanced physicochemical, structural, and magnetic characterization of multi-core particles, as well as single- and multi-core particle size distribution, morphology, internal structure, agglomerate formation processes, and constant and variable field magnetic properties. The review provides a comprehensive insight into the controlled synthesis and advanced structural and magnetic characterization of multi-core magnetic composites envisaged for nanomedicine and biotechnology. View Full-Text
Keywords: magnetic nanoparticle systems; ferrofluids; magnetic fluids; single core; multi-core; clusters; synthesis; functional coating; physical–chemical properties; structural characterization; magnetic characterization; small-angle scattering techniques; nanomedicine; biotechnology magnetic nanoparticle systems; ferrofluids; magnetic fluids; single core; multi-core; clusters; synthesis; functional coating; physical–chemical properties; structural characterization; magnetic characterization; small-angle scattering techniques; nanomedicine; biotechnology
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MDPI and ACS Style

Krasia-Christoforou, T.; Socoliuc, V.; Knudsen, K.D.; Tombácz, E.; Turcu, R.; Vékás, L. From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior. Nanomaterials 2020, 10, 2178. https://doi.org/10.3390/nano10112178

AMA Style

Krasia-Christoforou T, Socoliuc V, Knudsen KD, Tombácz E, Turcu R, Vékás L. From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior. Nanomaterials. 2020; 10(11):2178. https://doi.org/10.3390/nano10112178

Chicago/Turabian Style

Krasia-Christoforou, Theodora, Vlad Socoliuc, Kenneth D. Knudsen, Etelka Tombácz, Rodica Turcu, and Ladislau Vékás. 2020. "From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior" Nanomaterials 10, no. 11: 2178. https://doi.org/10.3390/nano10112178

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