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Recent Advances in Biomaterials for 3D Printing and Tissue Engineering
Article

Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems

1
Department of Mechanical Engineering, Aalto University, 02150 Espoo, Finland
2
Department of Otorhinolaryngology–Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, 00029 Helsinki, Finland
*
Author to whom correspondence should be addressed.
J. Funct. Biomater. 2018, 9(3), 41; https://doi.org/10.3390/jfb9030041
Received: 31 May 2018 / Revised: 26 June 2018 / Accepted: 27 June 2018 / Published: 29 June 2018
(This article belongs to the Special Issue 3D Printing of Biomaterials)
The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinity of target tissues or the selected medication route in a patient-specific manner as required. The identification and traceability of additively manufactured implants can be administered through radiofrequency identification systems. The focus of this study is to explore how embedded medication and sensors can be added in different additive manufacturing processes. The concept is extended to biomaterials with the help of the literature. As a result of this study, a patient-specific drug delivery device can be custom-designed and additively manufactured in the form of an implant that can identify, trace, and dispense a drug to the vicinity of a selected target tissue as a patient-specific function of time for bodily treatment and restoration. View Full-Text
Keywords: additive manufacturing; 3D printing; biomaterials; parametric modeling; drug delivery systems; embedding; medicine; radiofrequency identification; object memory; internet of things additive manufacturing; 3D printing; biomaterials; parametric modeling; drug delivery systems; embedding; medicine; radiofrequency identification; object memory; internet of things
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MDPI and ACS Style

Akmal, J.S.; Salmi, M.; Mäkitie, A.; Björkstrand, R.; Partanen, J. Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems. J. Funct. Biomater. 2018, 9, 41. https://doi.org/10.3390/jfb9030041

AMA Style

Akmal JS, Salmi M, Mäkitie A, Björkstrand R, Partanen J. Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems. Journal of Functional Biomaterials. 2018; 9(3):41. https://doi.org/10.3390/jfb9030041

Chicago/Turabian Style

Akmal, Jan S., Mika Salmi, Antti Mäkitie, Roy Björkstrand, and Jouni Partanen. 2018. "Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems" Journal of Functional Biomaterials 9, no. 3: 41. https://doi.org/10.3390/jfb9030041

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