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Open AccessArticle

Computational Modeling to Predict Fatigue Behavior of NiTi Stents: What Do We Need?

1
Laboratory of Biological Structure Mechanics, Department of Chemistry, Materials and Chemical Engineering 'Giulio Natta', Politecnico di Milano, Milan 20133, Italy
2
Department of Civil and Environmental Engineering, Politecnico di Milano, Milan 20133, Italy
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Francesco Puoci
J. Funct. Biomater. 2015, 6(2), 299-317; https://doi.org/10.3390/jfb6020299
Received: 31 March 2015 / Revised: 25 April 2015 / Accepted: 11 May 2015 / Published: 20 May 2015
(This article belongs to the Special Issue Biomedical Applications of Shape Memory Alloys)
NiTi (nickel-titanium) stents are nowadays commonly used for the percutaneous treatment of peripheral arterial disease. However, their effectiveness is still debated in the clinical field. In fact a peculiar cyclic biomechanical environment is created before and after stent implantation, with the risk of device fatigue failure. An accurate study of the device fatigue behavior is of primary importance to ensure a successful stenting procedure. Regulatory authorities recognize the possibility of performing computational analyses instead of experimental tests for the assessment of medical devices. However, confidence in numerical methods is only possible after verification and validation of the models used. For the case of NiTi stents, mechanical properties are strongly dependent on the device dimensions and the whole treatments undergone during manufacturing process. Hence, special attention should be paid to the accuracy of the description of the device geometry and the material properties implementation into the numerical code, as well as to the definition of the fatigue limit. In this paper, a path for setting up an effective numerical model for NiTi stent fatigue assessment is proposed and the results of its application in a specific case study are illustrated. View Full-Text
Keywords: peripheral arterial diseases; shape memory alloys; cardiovascular devices; fatigue failure; finite element analyses peripheral arterial diseases; shape memory alloys; cardiovascular devices; fatigue failure; finite element analyses
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MDPI and ACS Style

Dordoni, E.; Petrini, L.; Wu, W.; Migliavacca, F.; Dubini, G.; Pennati, G. Computational Modeling to Predict Fatigue Behavior of NiTi Stents: What Do We Need? J. Funct. Biomater. 2015, 6, 299-317. https://doi.org/10.3390/jfb6020299

AMA Style

Dordoni E, Petrini L, Wu W, Migliavacca F, Dubini G, Pennati G. Computational Modeling to Predict Fatigue Behavior of NiTi Stents: What Do We Need? Journal of Functional Biomaterials. 2015; 6(2):299-317. https://doi.org/10.3390/jfb6020299

Chicago/Turabian Style

Dordoni, Elena; Petrini, Lorenza; Wu, Wei; Migliavacca, Francesco; Dubini, Gabriele; Pennati, Giancarlo. 2015. "Computational Modeling to Predict Fatigue Behavior of NiTi Stents: What Do We Need?" J. Funct. Biomater. 6, no. 2: 299-317. https://doi.org/10.3390/jfb6020299

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