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Open AccessArticle

Enhanced Grid-Based Visual Analysis of Retinal Layer Thickness with Optical Coherence Tomography

1
Institute of Visual and Analytic Computing, University of Rostock, Albert-Einstein-Str. 22, 18059 Rostock, Germany
2
Department of Ophthalmology, University of Rostock, Doberaner Str. 140, 18057 Rostock, Germany
*
Author to whom correspondence should be addressed.
This paper is an extended version of our paper published in the 10th International Conference on Information Visualization Theory and Applications (IVAPP 2019).
Information 2019, 10(9), 266; https://doi.org/10.3390/info10090266
Received: 20 July 2019 / Revised: 15 August 2019 / Accepted: 21 August 2019 / Published: 23 August 2019
(This article belongs to the Special Issue Information Visualization Theory and Applications (IVAPP 2019))
Optical coherence tomography enables high-resolution 3D imaging of retinal layers in the human eye. The thickness of the layers is commonly assessed to understand a variety of retinal and systemic disorders. Yet, the thickness data are complex and currently need to be considerably reduced prior to further processing and analysis. This leads to a loss of information on localized variations in thickness, which is important for early detection of certain retinal diseases. We propose an enhanced grid-based reduction and exploration of retinal thickness data. Alternative grids are computed, their representation quality is rated, and best fitting grids for given thickness data are suggested. Selected grids are then visualized, adapted, and compared at different levels of granularity. A visual analysis tool bundles all computational, visual, and interactive means in a flexible user interface. We demonstrate the utility of our tool in a complementary analysis procedure, which eases the evaluation of ophthalmic study data. Ophthalmologists successfully applied our solution to study localized variations in thickness of retinal layers in patients with diabetes mellitus. View Full-Text
Keywords: visual analysis; optical coherence tomography; retina; layer thickness; early treatment diabetic retinopathy study; enhanced grids visual analysis; optical coherence tomography; retina; layer thickness; early treatment diabetic retinopathy study; enhanced grids
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MDPI and ACS Style

Röhlig, M.; Prakasam, R.K.; Stüwe, J.; Schmidt, C.; Stachs, O.; Schumann, H. Enhanced Grid-Based Visual Analysis of Retinal Layer Thickness with Optical Coherence Tomography. Information 2019, 10, 266.

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