Weekend Effect and in-Hospital Mortality in Elderly Patients with Acute Kidney Injury: A Retrospective Analysis of a National Hospital Database in Italy
Abstract
1. Introduction
2. Experimental Section
2.1. Patient Selection and Eligibility
2.2. Data Analysis
2.3. Statistical Analysis
3. Results
4. Discussion
Limitations
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Items | Score |
---|---|
Age 0–60 (years) | 0 |
Age 61–70 (years) | 3 |
Age 71–80 (years) | 7 |
Age 81–90 (years) | 11 |
Age 91+ (years) | 16 |
Chronic kidney disease | 1 |
Male gender | 2 |
Neurological disorders | 3 |
Lymphoma | 4 |
Solid tumor without metastasis | 4 |
Ischemic heart disease | 5 |
Congestive heart failure | 5 |
Coagulopathy | 8 |
Fluid and electrolyte disorders | 8 |
Liver disease | 10 |
Cachexia | 11 |
Metastatic cancer | 12 |
Total Number of Records | 760,664 |
---|---|
Men (n (%)) | 397,174 (52.2) |
Women (n (%)) | 361,490 (47.8) |
Age (years) | 80.5 ± 7.8 |
Comorbidity score | 14.57 ± 6.21 |
Dialysis dependent AKI (n (%)) | 68,563 (9) |
Patients admitted during WE (n (%)) | 184,727 (24.3) |
Deceased subjects (n (%)) | 210,661 (27.7) |
Survivors n = 550,003 | Deceased n = 210,661 | p | |
---|---|---|---|
Men (n (%)) | 288,120 (52.4) | 109,054 (51.8) | <0.001 |
Women (n (%)) | 261,883 (47.6) | 101,607 (48.2) | |
Age (years) | 80 ± 7.7 | 81.9 ± 7.9 | <0.001 |
Comorbidity score | 14.04 ± 6.02 | 15.96 ± 6.48 | <0.001 |
Dialysis dependent AKI (n (%)) | 37,598 (6.8) | 31,055 (17.7) | <0.001 |
Patients admitted during WE (n (%)) | 130,318 (23.7) | 54,409 (25.8) | <0.001 |
WD Admissions n = 575,937 | WE Admissions n = 184,727 | p | |
---|---|---|---|
Men (n (%)) | 302,010 (52.4) | 95,164 (51.5) | <0.001 |
Women (n (%)) | 273,927 (47.6) | 89,563 (48.5) | |
Age (years) | 80.4 ± 7.8 | 81 ± 7.8 | <0.001 |
Dialysis dependent AKI (n (%)) | 52,075 (9) | 16,578 (9) | NS |
Comorbidity score | 14.52 ± 6.22 | 14.75 ± 6.2 | <0.001 |
OR | 95% Confidence Intervals | p | |
---|---|---|---|
Dialysis dependent AKI | 2.711 | 2.667–2.755 | <0.001 |
WE admission | 1.113 | 1.100–1.126 | <0.001 |
Comorbidity score | 1.056 | 1.055–1.057 | <0.001 |
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Fabbian, F.; De Giorgi, A.; Di Simone, E.; Cappadona, R.; Lamberti, N.; Manfredini, F.; Boari, B.; Storari, A.; Manfredini, R. Weekend Effect and in-Hospital Mortality in Elderly Patients with Acute Kidney Injury: A Retrospective Analysis of a National Hospital Database in Italy. J. Clin. Med. 2020, 9, 1815. https://doi.org/10.3390/jcm9061815
Fabbian F, De Giorgi A, Di Simone E, Cappadona R, Lamberti N, Manfredini F, Boari B, Storari A, Manfredini R. Weekend Effect and in-Hospital Mortality in Elderly Patients with Acute Kidney Injury: A Retrospective Analysis of a National Hospital Database in Italy. Journal of Clinical Medicine. 2020; 9(6):1815. https://doi.org/10.3390/jcm9061815
Chicago/Turabian StyleFabbian, Fabio, Alfredo De Giorgi, Emanuele Di Simone, Rosaria Cappadona, Nicola Lamberti, Fabio Manfredini, Benedetta Boari, Alda Storari, and Roberto Manfredini. 2020. "Weekend Effect and in-Hospital Mortality in Elderly Patients with Acute Kidney Injury: A Retrospective Analysis of a National Hospital Database in Italy" Journal of Clinical Medicine 9, no. 6: 1815. https://doi.org/10.3390/jcm9061815
APA StyleFabbian, F., De Giorgi, A., Di Simone, E., Cappadona, R., Lamberti, N., Manfredini, F., Boari, B., Storari, A., & Manfredini, R. (2020). Weekend Effect and in-Hospital Mortality in Elderly Patients with Acute Kidney Injury: A Retrospective Analysis of a National Hospital Database in Italy. Journal of Clinical Medicine, 9(6), 1815. https://doi.org/10.3390/jcm9061815