Which MRI Score and Technique Should Be Used for Assessing Crohn’s Disease Activity?
1
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20090 Milan, Italy
2
Department of Gastroenterology and Inserm NGERE U1256, University Hospital of Nancy, University of Lorraine, 54500 Vandoeuvre-lès-Nancy, France
3
Department of Hepato-Gastroenterology, University Hospital of Grenoble, University of Grenoble Alpes, 38000 Grenoble, France
4
Department of Radiology, Nancy University Hospital, Lorraine University, 54500 Vandœuvre-lès-Nancy, France
5
IBD Center, Department of Gastroenterology, Humanitas Clinical and Research Center -IRCCS-, Rozzano, 20089 Milan, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(6), 1691; https://doi.org/10.3390/jcm9061691
Received: 30 April 2020
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Revised: 13 May 2020
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Accepted: 25 May 2020
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Published: 2 June 2020
(This article belongs to the Special Issue Novel Therapies and Approaches to Inflammatory Bowel Disease (IBD))
Magnetic resonance (MR) enterography is assuming an increasingly important and central role in the management of patients with Crohn’s disease, as it is not only involved in diagnosis and staging of the disease but also allows for patients’ follow-up, evaluating the response to therapy, and predicting disease outcomes. Several MR scores have been developed but unfortunately there is no globally accepted score. The most widely used scores are the Magnetic Resonance Index of Activity (MaRIA) score, the London score, the Nancy score, and the Clermont score; however, there are multiple differences between these tools in terms of the assessed radiological items, fasting, administration of oral or intravenous contrast, and the use of diffusion-weighted images. Here we reviewed the main characteristics of each MR scoring system to clarify which is the most appropriate score for monitoring disease activity in both clinical practice and clinical trials.
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Keywords:
MRI score; Crohn’s disease; disease activity
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MDPI and ACS Style
D’Amico, F.; Chateau, T.; Laurent, V.; Danese, S.; Peyrin-Biroulet, L. Which MRI Score and Technique Should Be Used for Assessing Crohn’s Disease Activity? J. Clin. Med. 2020, 9, 1691. https://doi.org/10.3390/jcm9061691
AMA Style
D’Amico F, Chateau T, Laurent V, Danese S, Peyrin-Biroulet L. Which MRI Score and Technique Should Be Used for Assessing Crohn’s Disease Activity? Journal of Clinical Medicine. 2020; 9(6):1691. https://doi.org/10.3390/jcm9061691
Chicago/Turabian StyleD’Amico, Ferdinando, Thomas Chateau, Valérie Laurent, Silvio Danese, and Laurent Peyrin-Biroulet. 2020. "Which MRI Score and Technique Should Be Used for Assessing Crohn’s Disease Activity?" Journal of Clinical Medicine 9, no. 6: 1691. https://doi.org/10.3390/jcm9061691
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