Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty
Abstract
1. Introduction
2. Patients and Methods
Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Conflicts of Interest
References
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Variables | Overall | DVT | No DVT | p Value # | |
---|---|---|---|---|---|
n | 500 | 26 | 474 | ||
Sex | Male | 91 | 2 | 89 | 0.12 |
Female | 409 | 24 | 385 | ||
Age, years | 64.79 ± 12.7 (22–89) | 70.0 ± 14.6 (35–87) | 64.5 ± 12.5 (22–89) | 0.0083 | |
BMI, kg/m2 | 24.0 ± 4.0 (12.2–41.7) | 23.6 ± 3.9 (18.2–32.2) | 24.3 ± 4.2 (12.2–41.8) | 0.63 | |
Current steroid use | 54 | 10/26 | 44/474 | <0.0001 | |
Previous DVT history | 11/500 | 6/26 | 5/474 | <0.0001 | |
Current anticoagulant use | 51/500 | 6/26 | 45/474 | 0.026 | |
Atrial fibrillation | 15/500 | 1/26 | 14/474 | 0.80 | |
Congestive heart failure | 16/500 | 1/26 | 15/474 | 0.85 | |
Major surgery | 347/500 | 20/26 | 327/474 | 0.22 | |
Major surgery within last 12 months | 70/500 | 7/26 | 63/474 | 0.053 | |
Diabetes mellitus | 54/500 | 3/26 | 51/474 | 0.9 | |
Collagen disease | 55/500 | 7/26 | 48/474 | 0.023 | |
Malignancy | 78/500 | 3/26 | 75/474 | 0.55 | |
Current smoking | 36/500 | 1/26 | 35/474/ | 0.50 |
Type of Collagen Disease | Overall (n = 500) | DVT (n = 26) | No DVT (n = 474) |
---|---|---|---|
Rheumatoid arthritis | 23 | 2 | 21 |
Systemic lupus erythematosus | 15 | 2 | 13 |
Dermatomyositis | 8 | 1 | 7 |
Systemic sclerosis | 3 | 3 | 0 |
Sjögren syndrome | 3 | 0 | 3 |
Polymyalgia rheumatica | 2 | 0 | 2 |
Polyarteritis nodosa | 1 | 0 | 1 |
Adult Still’s disease | 1 | 0 | 1 |
Behçet’s disease | 1 | 0 | 1 |
Eosinophilic granulomatosis with polyangiitis | 1 | 0 | 1 |
Variables | Overall | DVT | No DVT | p Value # |
---|---|---|---|---|
Oxford Hip Score | 29.4 ± 10.2 | 22.5 ± 12.3 | 29.7 ± 10.0 | 0.0060 |
Harris Hip Score | 52.6 ± 16.1 | 50.9 ± 17.8 | 52.7 ± 16.0 | 0.55 |
UCLA activity score | 3.69 ± 1.34 | 2.64 ± 0.91 | 3.75 ± 1.33 | <0.0001 |
VAS | 6.08 ± 2.81 | 6.88 ± 2.50 | 6.04 ± 2.82 | 0.21 |
UCLA | OHS | HHS | VAS | |
---|---|---|---|---|
UCLA | <0.0001 | <0.0001 | <0.0001 | 0.0039 |
OHS | <0.0001 | <0.0001 | <0.0001 | |
HHS | <0.0001 | 0.0032 | ||
VAS | <0.0001 |
UCLA | OHS | HHS | VAS | |
---|---|---|---|---|
UCLA | 1.0 | 0.34 | 0.43 | −0.14 |
OHS | 1.0 | 0.42 | −0.60 | |
HHS | 1.0 | −0.31 | ||
VAS | 1.0 |
Variables | Odds Ratio | 95% CI | p Value | VIF |
---|---|---|---|---|
OHS | 0.95 | 0.91–0.99 | 0.031 | 1.02 |
Age | 1.07 | 1.03–1.12 | 0.00056 | 1.12 |
Previous history of DVT | 27.15 | 3.31–222.53 | 0.0021 | 1.18 |
Current anticoagulant use | 0.48 | 0.09–2.63 | 0.39 | 1.20 |
Collagen disease | 0.93 | 0.19–4.64 | 0.93 | 1.60 |
Current steroid use | 10.45 | 2.31–47.34 | 0.0023 | 1.67 |
Variables | Odds Ratio | 95% CI | p Value | VIF |
---|---|---|---|---|
UCLA activity score | 0.49 | 0.28–0.84 | 0.0099 | 1.16 |
Age | 1.07 | 1.02–1.12 | 0.0027 | 1.27 |
Previous history of DVT | 74.98 | 8.54–658.18 | <0.0001 | 1.17 |
Current anticoagulant use | 0.34 | 0.056–2.06 | 0.24 | 1.20 |
Collagen disease | 1.03 | 0.23–4.68 | 0.97 | 1.55 |
Current steroid use | 9.32 | 2.14–40.68 | 0.0030 | 1.69 |
Variables | AUC | Youden Index | Predictive Cutoff | Sensitivity | Specificity | PPV (%) | NPV (%) |
---|---|---|---|---|---|---|---|
UCLA activity score | 0.755 | 0.393 | 2 | 56.0 | 83.3 | 15.7 | 94.7 |
OHS | 0.673 | 0.312 | 22 | 54.5 | 76.6 | 10.4 | 97.1 |
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Kawai, T.; Goto, K.; Kuroda, Y.; Matsuda, S. Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty. J. Clin. Med. 2020, 9, 1257. https://doi.org/10.3390/jcm9051257
Kawai T, Goto K, Kuroda Y, Matsuda S. Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty. Journal of Clinical Medicine. 2020; 9(5):1257. https://doi.org/10.3390/jcm9051257
Chicago/Turabian StyleKawai, Toshiyuki, Koji Goto, Yutaka Kuroda, and Shuichi Matsuda. 2020. "Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty" Journal of Clinical Medicine 9, no. 5: 1257. https://doi.org/10.3390/jcm9051257
APA StyleKawai, T., Goto, K., Kuroda, Y., & Matsuda, S. (2020). Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty. Journal of Clinical Medicine, 9(5), 1257. https://doi.org/10.3390/jcm9051257