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Strategies to Prevent Cardiovascular Toxicity in Breast Cancer: Is It Ready for Primetime?

1
Division of Medical Oncology, Duke Cancer Institute, Duke University, Durham, NC 27710, USA
2
Division of Cardiology, Duke Heart Center, Duke University, Durham, NC 27710, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(4), 896; https://doi.org/10.3390/jcm9040896
Received: 26 February 2020 / Revised: 16 March 2020 / Accepted: 20 March 2020 / Published: 25 March 2020
Cardio-oncology is an emerging field tasked with identifying and treating cancer therapy related cardiac dysfunction (e.g., cytotoxic agents, immunotherapies, radiation, and hormone therapies) and optimizing the cardiovascular health of cancer patients exposed to these agents. Novel cancer therapies have led to significant improvements in clinical outcomes for breast cancer patients. In this article, we review the current literature on assessing cardiovascular risk of breast cancer therapies and discuss strategies (including pharmacological and lifestyle interventions) to prevent cardiovascular toxicity. View Full-Text
Keywords: Cardio-oncology; cardiotoxicity; oncology; cardiology; primary prevention; breast cancer; anthracyclines; trastuzumab Cardio-oncology; cardiotoxicity; oncology; cardiology; primary prevention; breast cancer; anthracyclines; trastuzumab
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Kikuchi, R.; Shah, N.P.; Dent, S.F. Strategies to Prevent Cardiovascular Toxicity in Breast Cancer: Is It Ready for Primetime? J. Clin. Med. 2020, 9, 896.

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