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Cognition in Children with Arachnoid Cysts

Section for Neurosurgery, Department of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
Neuropediatric Unit, Astrid Lindgren Children’s Hospital, Karolinska University Hospital, 171 76 Stockholm, Sweden
Department of Women’s and Children’s Health, Karolinska Institutet, 171 77 Stockholm, Sweden
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(3), 850;
Received: 3 March 2020 / Revised: 18 March 2020 / Accepted: 19 March 2020 / Published: 20 March 2020
(This article belongs to the Section Clinical Neurology)
Background: This study aims to evaluate if children with temporal arachnoid cysts (AC) have cognitive symptoms and if neurosurgery improves these. Methods: A prospective case series study including consecutive pediatric patients with temporal AC. The children underwent neuroradiology, neuroopthalmologic evaluation, and a standard electroencephalography (EEG). Additionally, a neuropsychologist performed a standardized set of evaluations, with a one-year follow-up consisting of Weschler Intelligence Scale for Children version IV (WISC-IV), FAS (for verbal fluency), Boston Naming Test (BNT, for visual naming ability) and NEPSY-II (Developmental NEuroPSYchological Assessment) for verbal memory. Results: Fifteen children, 9 boys and 6 girls, were evaluated and 11 underwent surgery. The Full Scale IQ subscore (FSIQ) improved from M = 84.8 to M = 93.0 (p = 0.005). The preoperative Verbal Comprehension Index (VCI) was in the low average range (M = 86.7), improving to a level within the average range (M = 94.7, p = 0.001). Preoperative Perceptual Speed Index (PSI) was in the below average range (M = 81.5), improving to a level within the average range (M = 92.5, p = 0.004). Conclusion: ACs are a common finding in a pediatric neurosurgical setting. Our data suggest that some temporal AC have a negative effect on general cognitive ability and that this impairment can be improved by surgery. We suggest a standardized evaluation, including comprehensive and validated neuropsychological assessment tools, to thoroughly assess symptoms as well as the postoperative outcome. View Full-Text
Keywords: arachnoid cyst; cognition; neuropsychology; pediatric neurosurgery; neurosurgery arachnoid cyst; cognition; neuropsychology; pediatric neurosurgery; neurosurgery
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Sandvik, U.; Adolfsson, T.; Jacobson, D.N.; Tedroff, K. Cognition in Children with Arachnoid Cysts. J. Clin. Med. 2020, 9, 850.

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