Next Article in Journal
Role of Mesenchymal Stromal Cells as Therapeutic Agents: Potential Mechanisms of Action and Implications in Their Clinical Use
Previous Article in Journal
Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients for the Treatment of Severe Aortic Stenosis

Outcomes of Vitrectomy for Long-Duration Macular Hole

Eye Hospital, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia
Faculty of Dentistry, University of Oslo, 0317 Oslo, Norway
Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and University of Oslo, 0450 Oslo, Norway
Author to whom correspondence should be addressed.
These authors are shared last authors.
J. Clin. Med. 2020, 9(2), 444;
Received: 21 December 2019 / Revised: 31 January 2020 / Accepted: 1 February 2020 / Published: 6 February 2020
(This article belongs to the Section Ophthalmology)
The present study investigated the functional and anatomical outcomes of idiopathic chronic macular hole (MH) surgery with different surgical approaches related to the chronicity and diameter of the MH. A comparative retrospective study between three groups of patients who underwent vitrectomy for long-duration MH (mean: 13.5 months) was conducted. In the first group of patients (G1 or IP), the internal limiting membrane (ILM) was systematically peeled; in the second group (G2 or IPEP), the ILM and epiretinal membrane (ERM) were peeled; and in the third group (G3 or IF), patients underwent inverted ILM flap technique surgery. Pre- and post-operative best corrected visual acuities (pre- and post-op BCVA) were studied. Macular optical coherence tomography (OCT) scans were performed to measure the MH minimum and maximum diameter pre-operatively, as well as to confirm its post-op closure and evaluate the integrity of the ellipsoid zone (EZ). Fifty eyes of 48 patients (33 female and 15 male) were retrospectively evaluated. MH closure rate was 100% in IP group, 66.7% in IPEP, and 95.2% in IF group. All three groups had a statistically significant improvement of BCVA. EZ post-op was restored in 88.2% of the cases from G1, 41.6% from G2, and 23.8% from G3. No statistically significant relationship between the smaller or larger MH diameter and the visual acuity improvement was found. Patients with chronic MH and ERM have worse functional and anatomical outcomes after surgery. Treatment of chronic MHs without ERM results in a better closure rate with either an inverted ILM flap approach or systematic ILM peel. View Full-Text
Keywords: macular hole; visual acuity; macular hole diameter; ellipsoid zone macular hole; visual acuity; macular hole diameter; ellipsoid zone
Show Figures

Figure 1

MDPI and ACS Style

Lumi, X.; Mahnic, M.; Petrovski, B.É.; Petrovski, G. Outcomes of Vitrectomy for Long-Duration Macular Hole. J. Clin. Med. 2020, 9, 444.

AMA Style

Lumi X, Mahnic M, Petrovski BÉ, Petrovski G. Outcomes of Vitrectomy for Long-Duration Macular Hole. Journal of Clinical Medicine. 2020; 9(2):444.

Chicago/Turabian Style

Lumi, Xhevat, Mina Mahnic, Beáta É. Petrovski, and Goran Petrovski. 2020. "Outcomes of Vitrectomy for Long-Duration Macular Hole" Journal of Clinical Medicine 9, no. 2: 444.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop