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Article

Early Recovery of Left Ventricular Function After Revascularization in Acute Coronary Syndrome

1
Institute of Public Health and Clinical Medicine, Umea University, 90187 Umea, Sweden
2
International Cardiac Centre—ICC and Alexandria University, Alexandria 21500, Egypt
3
Cardiology Department, Faculty of Medicine, Alexandria University, Alexandria 21500, Egypt
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(1), 24; https://doi.org/10.3390/jcm9010024
Received: 6 November 2019 / Revised: 7 December 2019 / Accepted: 16 December 2019 / Published: 20 December 2019
(This article belongs to the Section Cardiology)
The aim of this study was to assess the accuracy of echocardiographic techniques in detecting the early recovery of left ventricular (LV) function after revascularization in acute coronary syndrome (ACS). In 80 consecutive patients with ACS (age 55.7 ± 9.4 years, 77% male, 15% with CCS Angina III), an echocardiographic examination of left ventricle regional wall motion abnormalities (LV RWMA), peak systolic strain rate (PSSR), peak systolic strain (PSS) and end systolic strain (ESS) was performed before and after percutaneous intervention (PCI). Of the 80 patients, one vessel stenosis (>70%) was present in 53 (66%), two vessel disease in 12 (15%) and multivessel disease in 15 patients (19%). In total, 51% of patients had hypertension, 40% diabetes and 23% dyslipidemia. After PCI, regional PSS, ESS and PSSR of their segments subtended by the culprit vessel improved; left anterior descending-LAD, circumflex-LCx and right coronary-RCA (p<0.05 for all) as well as global S and SR (p < 0.05 for all). In univariate analysis, hypertension (HTN) (β = −0.294 (−0.313–0.047), p = 0.009, smoking β = −0.244 (−0.289–0.015) =0.03, WMA β = −0.317 (−0.284–0.014), p = 0.004 and the number of diseased vessels β = −0.256 (−0.188– 0.054) p=0.03 were predictors of delta global SR. In multivariate analysis, only HTN β = 0.263 (0.005–3.159) and the number of diseased vessels β =0.263 (0.005 - 3.159), p=0.04) predicted delta global SR. In ACS, the echocardiographic regional myocardial deformation is accurate in detecting early recovery of LV myocardial function after culprit lesion revascularization. Also, the findings of this study support the current practice regarding the crucial importance of proximal epicardial vessel PCI treatment on LV function compared to more distal lesions. View Full-Text
Keywords: acute coronary syndrome; deformation parameters; left ventricular function acute coronary syndrome; deformation parameters; left ventricular function
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MDPI and ACS Style

Shenouda, R.; Bytyçi, I.; Sobhy, M.; Henein, M.Y. Early Recovery of Left Ventricular Function After Revascularization in Acute Coronary Syndrome. J. Clin. Med. 2020, 9, 24. https://doi.org/10.3390/jcm9010024

AMA Style

Shenouda R, Bytyçi I, Sobhy M, Henein MY. Early Recovery of Left Ventricular Function After Revascularization in Acute Coronary Syndrome. Journal of Clinical Medicine. 2020; 9(1):24. https://doi.org/10.3390/jcm9010024

Chicago/Turabian Style

Shenouda, Rafik; Bytyçi, Ibadete; Sobhy, Mohamed; Henein, Michael Y. 2020. "Early Recovery of Left Ventricular Function After Revascularization in Acute Coronary Syndrome" J. Clin. Med. 9, no. 1: 24. https://doi.org/10.3390/jcm9010024

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